Protein Alignment CROT and cpt-6

DIOPT Version :10

• Sequence 1: NP_733230.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_504648.1
• Gene: cpt-6 / 179035
• WormBaseID: WBGene00020911
• Length: 746
• Species: Caenorhabditis elegans
• Alignment Length: 656
• Identity: 162/656 - (24%)
• Similarity: 265/656 - (40%)
• Gaps: 123/656 - (18%)

  Fly    20 DETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMRNWL 84
            |..|||||:|.|:||:..|...::...:::|.....|...||....|.:|.......:....|::
 Worm   145 DRLLPSLPVPALKDTISEYLDSMKHILSEQEYEIVAKQAHEFLENEGKKLQRYTWIYSLFTDNYV 209

  Fly    85 GTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTRKSS--- 146
            .::|:.|.|...|.||:                              |:.|:...||.|...
 Worm   210 TSFWQKYAYLHGRYPLM------------------------------INSSVAHCDLLRDKEATR 244

  Fly   147 ---------IKPLSSNGGKIKYSSAL---------YKHFFSTCRVPGEEQDHIEKHFLTKDEGKT 193
                     |:.:|......:...||         ||:.::..|.||::.|.:..|.:.|
 Worm   245 AHRAARVTWIEVMSHLAIDRQQYKALGDGLVCTRHYKNMYAVTREPGKKIDQLILHGIQK----- 304

  Fly   194 PSHMLISGKGRQFIFDCVHEDDTILSAPEILVALQRVRSILDYEP--LGDCVPTLSHDERSTWAR 256
              |:::..:|:.:....|.:.:.|.:..::......:.|..:.|.  :|. :..|:||.|.:|.|
 Worm   305 --HIVVVLRGKYYKIHVVDDKNNIYTVEQLTKIFHEMISRDEKEEGVIGK-IAALTHDTRDSWHR 366

  Fly   257 NRNRLREISVANKETLLLVESACMEICWYEQSPKDYEE-----------SCQLGLYGDLHSRWAD 310
            ||.:....:|.|.:.|..:|.|.......|.....|:|           :|   |.||..:||.|
 Worm   367 NRQKYFLGNVKNAQILKEIECAVFFFTLDENDDYGYDEKKPEVLSNFLANC---LSGDGTNRWVD 428

  Fly   311 RSSSIIAFRNGRCNWTGEHSCYDGT------VSISYATFMQLSFLEVPEPDWAEAEKGNVLEVKE 369
            :|.:.|..:|.||..|.|||..||.      .:..|.....|.:..:     .|.||..|:|..:
 Worm   429 KSLNYICSKNARCGGTTEHSIADGAEFDHIMENFVYVDLEVLKYKSI-----EEQEKMAVIEEND 488

  Fly   370 ---------LHFQL-DDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQV 424
                     |:|:: |..:.:||.|..........|:.:...||.|:||..:|...:.||:|:|:
 Worm   489 KKSLKLATPLNFEVPDQEMLSEITRCYDAHQIAKNDLDLYALAFRDFGKGRIKKCGVSPDAFIQM 553

  Fly   425 VMQWAYYQMHKEIAPTYETALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAV 489
            .:|.|.|:...:...|||.|..|.:.|.||||||:......||:.|..|......:.....::|.
 Worm   554 AIQLANYRDQGKFVLTYEPASARFFANSRTETLRTVNDHSCEFVEAMLNANETKEAKIALLKKAC 618

  Fly   490 DEHKHFMNEARKGHGIDRHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTAN- 553
            :.|.....:...|.|:|||||.|:..:..:.:..| |.|:.:..|      :.||:|.:....|
 Worm   619 ETHVLRNKKCMVGQGVDRHLFVLYILSQGTGIQSP-FLDNYINQK------WKLSTSHVPNVTNQ 676

  Fly   554 ---------------VGFVAPMVFDGYGVFYSI-TSEAVFINTTAYRDSLKTSARKFNDIFKDSF 602
                           .|.||.   ||||:.|.. .:..:|.|.|:|..:..|.:.||..:..:||
 Worm   677 CDEDTDSDNTWLGACFGAVAA---DGYGICYRFGGNHGIFANITSYHSAANTDSTKFAKLLSESF 738

  Fly   603 RRISVL 608
            ..:|.|
 Worm   739 HELSNL 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_733230.1	Carn_acyltransf	26..594	CDD:459926	152/634 (24%)
cpt-6	NP_504648.1	Carn_acyltransf	151..736	CDD:459926	154/640 (24%)