Protein Alignment CROT and cpt-1

DIOPT Version :10

• Sequence 1: NP_733230.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_496721.2
• Gene: cpt-1 / 174912
• WormBaseID: WBGene00012907
• Length: 779
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 174/648 - (26%)
• Similarity: 294/648 - (45%)
• Gaps: 61/648 - (9%)

  Fly     6 LYFMSKDDKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLH 70
            |:.:||.......|...||.||||.|.||:.::...::|..:.||..:.....:.|:.|||.:|.
 Worm   155 LHIISKAGPMLHSFQGALPRLPLPNLDDTVRKHLLSMKPILSDEEFQELEFLSERFRKGVGRRLQ 219

  Fly    71 EQLKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARHI-HH 134
            ..|..::....|::..|||::.|...|.|     :|:..:......:.|.|.....|.|.:: :.
 Worm   220 RYLTLKSWFSSNYVTDWWEEFVYMRQRSP-----IMINSNYYGFDTLNEHPTQNQASRAANLTYT 279

  Fly   135 SLEFWDLTRKSSIKPLS-SNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHML 198
            ||:|..:..:..:.|.| |...|:.:.:..|:..|:||||||||.|.:    |..|:.|   |:.
 Worm   280 SLQFRRMVDRQEVSPFSISPRTKVPFCTMQYERLFNTCRVPGEEVDRL----LHWDDAK---HIA 337

  Fly   199 ISGKGRQFIFDCVHEDDTILSAPEILVALQRVRSILDYEPLGDC-VPTLSHDERSTWARNRNRLR 262
            :..:|..|.. .||....:|.|.|:.|....:.:.......|:. :.:|:..||:.||:.| |..
 Worm   338 VYCRGVWFKL-IVHNGKRLLEACELQVQYDAILAHTHEPSEGEMHLASLTAGERADWAKTR-RAH 400

  Fly   263 EISVANKETLLLVESACM-------EICWYEQSPKDYEESCQLGLYGDLHSRWADRSSSIIAFRN 320
            ..|..||.:|..:|.|..       |..:..|.|...:......|:|..|.||.|:|.::|..:|
 Worm   401 FRSGVNKTSLNDIERAAFVVILDDEETHYDPQDPSKLDHWAHNLLHGKAHDRWFDKSFNLIISKN 465

  Fly   321 GRCNWTGEHSCYDGTVSISYATFMQLS---FLEVPEPDWAEAEKGNVLEVKELHFQLDDTLKNEI 382
            |......|||..|..|...:..:..|.   |:...|....:.|....|..:.|.:::.....::|
 Worm   466 GHVGINTEHSWGDAAVMAHFTEWSLLQDIVFIGYDENGRCKGEPKEKLTPERLKWEIPAPALDQI 530

  Fly   383 KRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALMR 447
            ::..:..:....||.::...:.||||.|.|..::.||:|:|:.:|:.|::...:.:.|||.::.|
 Worm   531 RKSMEVANALIADVEMSLLVWTDYGKGFAKKLKVSPDAFLQMTLQYTYFKNQNKFSLTYEASMTR 595

  Fly   448 QYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHLFGL 512
            .:..|||||:||||...::|:|:..:.........:..|:|.|:|:....:|..|.|:|||||.|
 Worm   596 LFREGRTETVRSCTVQSSDFVRSMLDASKTPQDRLQLLRKACDKHQELYRDAMCGQGVDRHLFAL 660

  Fly   513 WCAAYESKMDIPAFYDD---PMYTKSGGGGNFVLSSSTLG-------------------FTANVG 555
            :......:.:.| |:|:   |.|         :||:|...                   .||..|
 Worm   661 YVIKRYLEEESP-FFDNIFPPTY---------LLSTSQTPMNQCEADAKGLSNEVRLRLITAGGG 715

  Fly   556 FVAPMVFDGYGVFYSITSE-AVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLEQLAKESK 617
            | .|:...||||.|.:..| .:..:.::.|.:..||:|:|.:..|.|...:..|.|.:....|
 Worm   716 F-GPVADRGYGVSYIVAGEDTLSFHISSKRSADNTSSREFREELKRSLNDMKKLAEAIEAPKK 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_733230.1	Carn_acyltransf	26..594	CDD:459926	162/603 (27%)
cpt-1	NP_496721.2	CPT_N	1..47	CDD:465132
		Carn_acyltransf	175..760	CDD:459926	163/609 (27%)