Protein Alignment CROT and Crat

DIOPT Version :10

• Sequence 1: NP_733230.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_001407005.1
• Gene: Crat / 12908
• MGIID: 109501
• Length: 631
• Species: Mus musculus
• Alignment Length: 625
• Identity: 170/625 - (27%)
• Similarity: 310/625 - (49%)
• Gaps: 68/625 - (10%)

  Fly    21 ETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQ--NGVGAQLHEQLKKRAAGMRNW 83
            :.||.||:|.|:.:::.|...:||..::||.|..::.:||||  .|||.:|.:.|::||..|.||
Mouse    33 DALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENW 97

  Fly    84 LGTWWEDYGYHLIRMPLLPYQL--MVMPSQ--LEMVGVPETPEYMLKSLARHIHHSLEFWDLTRK 144
            |..||....|...|.|::.|..  :::|.|  :::.|       .|:..|:.|...|:|..:...
Mouse    98 LSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQG-------QLRFAAKLIEGVLDFKSMIDN 155

  Fly   145 SSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFD 209
            .:: |:...||:....:..|: ..|:|||||.:||.:.....:|   :.|:|:.:....:.|..|
Mouse   156 ETL-PVEFLGGQPLCMNQYYQ-ILSSCRVPGPKQDSVVNFLKSK---RPPTHITVVHNYQFFELD 215

  Fly   210 CVHEDDTILSAPEILVALQRV-RSIL--DYEPLGDCVPTLSHDERSTWARNRNRLREISVANKET 271
            ..|.|.|.|::.:|.|.|::: .|.|  :.||:|    .|:.:.|:|||:..|.|.:..| |:|:
Mouse   216 VYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVG----ILTSNHRNTWAKAYNNLIKDKV-NRES 275

  Fly   272 LLLVESACMEICWYEQSPKDYEESCQLGLYGD-LH---------SRWADRSSSIIAFRNGRCNWT 326
            :..::.:...:|..:|.|:..::..:..:.|. ||         :||.|::...|...:|.|...
Mouse   276 VNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMV 340

  Fly   327 GEHSCYDGTVSISYA----------TFMQLSFLEVPEPDWAEAEKGNVLEVKELHFQLDDTLKNE 381
            .||:..:|...::..          ..::...:.:|.|             |:|.|.:...:||:
Mouse   341 YEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMP-------------KKLRFNITPEIKND 392

  Fly   382 IKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALM 446
            |::.::::.....|:.:....|..:||||.|:.:|.||:|:||.:|.|||:::.:...|||:|.:
Mouse   393 IEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASL 457

  Fly   447 RQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMN-----EARKGHGID 506
            |.::.|||:|:||.:.....|::...:..|.:.......|:||..|:.:.:     :|.:|...|
Mouse   458 RMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRISHPQAIRGEAFD 522

  Fly   507 RHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTL-GFTANVGFVAPMVFDGYGVFYS 570
            |||.||...|.|..:.:|..:.|..|..:   .:|.||:|.: ..|..|.|..|:|.||||:.|:
Mouse   523 RHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHFNLSTSQVPAKTDCVMFFGPVVPDGYGICYN 584

  Fly   571 ITSEAVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLE 610
            .....:..:.:||....:|:|.:.....:.:...:..||:
Mouse   585 PMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQ 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_733230.1	Carn_acyltransf	26..594	CDD:459926	166/602 (28%)
Crat	NP_001407005.1	Carn_acyltransf	38..614	CDD:459926	166/608 (27%)
		Microbody targeting signal. /evidence=ECO:0000255	629..631