Protein Alignment btz and casc3

DIOPT Version :10

• Sequence 1: NP_001263028.1
• Gene: btz / 43331
• FlyBaseID: FBgn0045862
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_012827180.2
• Gene: casc3 / 503560
• XenbaseID: XB-GENE-969211
• Length: 700
• Species: Xenopus tropicalis
• Alignment Length: 759
• Identity: 180/759 - (23%)
• Similarity: 276/759 - (36%)
• Gaps: 250/759 - (32%)

  Fly    42 EPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDED------- 99
            ||||...:.|....   :||.::...:||.....|.|||      ...|||:...:|:
 Frog    44 EPGTKRAEPPREGK---ESECESEDGIEGDAVLSDYESA------ESEEEEAHLSEEEPLKTTLK 99

  Fly   100 -------------------DEVGSETDDGEGEQAM--DRSVADSEAQKKV--DEDRSNPQYIPKR 141
                               ..|..|...|:|:::.  :.:....::||::  ||||.||.|||::
 Frog   100 QENNVEEAPATREQKPKSKGAVTGERQSGDGQESTEPEENKTSKKSQKQLDDDEDRKNPAYIPRK 164

  Fly   142 GTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQP 206
            |.|:|||.|....:.|:                           .|.|:.|:        :.|:.
 Frog   165 GLFFEHDLRGHVNDEEV---------------------------RPKGRHPR--------KLWKD 194

  Fly   207 ASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIR----NEDAPPRARRRRRY---------TRGP 258
            ..   ||.||||...|||||||.||:..||||||    :|:..||..|:.|:         :..|
 Frog   195 EG---RWEHDRFREDEQAPKSREELISIYGYDIRSSKNSEEIRPRRPRKPRFGSPTRREEISEKP 256

  Fly   259 SKYSRNWEDEQAYLKASNKERKPPRP---QDFPALNERKPRGPRTSSSRE--EKENRRSVAAEGL 318
            |:.|..::|...        .:|.||   ::.|..|:   .||..:.||:  .||||.|..:|..
 Frog   257 SRPSNRYQDSGI--------SQPLRPYTNRNAPPSNK---VGPSRTYSRQGGYKENRSSYQSEEE 310

  Fly   319 VPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRE 383
            .|           ||.|:.|:                ::|                   |.:.|.
 Frog   311 AP-----------PHPSERRQ----------------DYG-------------------GHRARS 329

  Fly   384 RERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQ-QSPQTPLSTSNLSQ-RLQ 446
            .|:|          |:.||   :..|:..|..:::|..::|.::|. ..|..|:...:.|: |..
 Frog   330 TEQG----------PAPPR---EFSPEADPIIKEEPVIEKQAAEPSPPPPDRPVEKKSYSRVRRS 381

  Fly   447 QVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQ----PLHQEQRN-APKRYSSLRRSQQEASQ-HL 505
            :::..:....:....:..|......|.....:    ||:.:|.| .|.....:...::|.|| :|
 Frog   382 RIKVGDTGKSMEDTTVTELPPPPPVPPAVAAEFTPAPLNVKQGNWEPPSEGGMSGIEEELSQMNL 446

  Fly   506 AEQQQQQMQ----------QQLHL------------------QQQQQQQQSQIMIQDP---HVLM 539
            :||.....|          ..:|:                  :.::...|.|..:.||   |:.:
 Frog   447 SEQSWNPGQPAYISPRGIPNPMHMGGGPPQYNRMEGMAVQGGRVKRYSTQRQRPVPDPAAMHISL 511

  Fly   540 QIAYQQQELQAQLQTMQLGPPTAAGAVPT--PPK----------------PHAPPAA-AYPQAQA 585
            ..::....||.|      ||..|.|..|:  ||:                ||.|||. :.|....
 Frog   512 MESHYYDPLQFQ------GPIYAHGDSPSSMPPQGMIVQPEMHLSHPGIHPHQPPATISTPNLYP 570

  Fly   586 APYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQP 650
            ||..:...:|.|..:...||.         |.|..|  ...|.|  |.|.||.|..||   |...
 Frog   571 APVSLPPGQPPPQQLLPPPYF---------TAPPNV--MNFGNP--TYPYPPGALPPP---PTHL 619

  Fly   651 YQN----YNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPP 690
            |.|    ....||.||: .|.|...:|...|.||.:..:.|.||
 Frog   620 YPNAQAQSQVYGGVTYY-NPVQQQVQPKPSPPRRTSQPVTIKPP 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btz	NP_001263028.1	Btz	102..243	CDD:214991	47/148 (32%)
casc3	XP_012827180.2	Btz	125..228	CDD:214991	45/140 (32%)