| Sequence 1: | NP_001263028.1 | Gene: | btz / 43331 | FlyBaseID: | FBgn0045862 | Length: | 806 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_671485.1 | Gene: | Casc3 / 259170 | RGDID: | 628766 | Length: | 699 | Species: | Rattus norvegicus |
| Alignment Length: | 764 | Identity: | 186/764 - (24%) |
|---|---|---|---|
| Similarity: | 276/764 - (36%) | Gaps: | 231/764 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 41 VEPGTSPTQEPNSNSHPHD--------SEYDTASDLEGGEDYDDEES--------ASGSASGSGS 89
Fly 90 EEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKK------VDEDRSNPQYIPKRGTFYEHD 148
Fly 149 DRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRW 213
Fly 214 SHDRFEATEQAPKSRAELLQTYGYDIRN----EDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKA 274
Fly 275 SNKERK--------PPRPQDFPALNERKPRGPRTSSSREE------KENR---RSVAAEGLVPEK 322
Fly 323 QQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQ-------------------N 368
Fly 369 GMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQ 433
Fly 434 TPL--STSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQ-QQPLHQEQRNAPKRYSSLR 495
Fly 496 RSQQEASQHLAEQQQQQM--QQQLHLQQ---QQQQQQSQIMIQDP-----HVLMQIAYQQQELQA 550
Fly 551 QLQTMQLGPPTAAGAVPTP---------PKPHAPPAAAYPQAQAAPYYVTGTEPVPV------PV 600
Fly 601 PQ---------APYV----NPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQ-PAQPY 651
Fly 652 QNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGA 700 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| btz | NP_001263028.1 | DUF3597 | 2..>43 | CDD:289008 | 1/1 (100%) |
| Btz | 102..243 | CDD:214991 | 46/150 (31%) | ||
| Casc3 | NP_671485.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..455 | 111/460 (24%) | |
| Necessary for RNA-binding, interaction with MAGOH and localization in nucleus speckles. /evidence=ECO:0000250 | 134..280 | 56/192 (29%) | |||
| Sufficient to form the EJC. /evidence=ECO:0000250 | 134..280 | 56/192 (29%) | |||
| Btz | 143..245 | CDD:214991 | 44/142 (31%) | ||
| Nuclear localization signal 1. /evidence=ECO:0000255 | 201..207 | 2/28 (7%) | |||
| Nuclear localization signal 2. /evidence=ECO:0000255 | 251..259 | 3/7 (43%) | |||
| Necessary for localization in cytoplasmic stress granules. /evidence=ECO:0000250 | 374..699 | 85/393 (22%) | |||
| Nuclear export signal | 458..467 | 3/23 (13%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 577..596 | 5/18 (28%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 629..699 | 29/92 (32%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166349235 | |
| Domainoid | 1 | 1.000 | 67 | 1.000 | Domainoid score | I9657 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4264 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 132 | 1.000 | Inparanoid score | I4517 |
| OMA | 1 | 1.010 | - | - | QHG47723 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0005383 | |
| OrthoInspector | 1 | 1.000 | - | - | oto98153 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | LDO | PTHR13434 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X4312 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.990 | |||||