| Sequence 1: | NP_001263028.1 | Gene: | btz / 43331 | FlyBaseID: | FBgn0045862 | Length: | 806 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031385.2 | Gene: | CASC3 / 22794 | HGNCID: | 17040 | Length: | 703 | Species: | Homo sapiens |
| Alignment Length: | 761 | Identity: | 189/761 - (24%) |
|---|---|---|---|
| Similarity: | 271/761 - (35%) | Gaps: | 222/761 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 41 VEPGTSPTQEPNSNSHPHD--------SEYDTASDLEGGE-DYDDEE-------SASGSASGSGS 89
Fly 90 EEE--SETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKK------VDEDRSNPQYIPKRGTFYE 146
Fly 147 HDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGD 211
Fly 212 RWSHDRFEATEQAPKSRAELLQTYGYDIRN----EDAPPRARRRRRYTRGPSKYSRNWEDEQAYL 272
Fly 273 KASNKER-----KPPRPQDFPALNERKPRGPRTSSSREE------KENR---RSVAAEGLVPEKQ 323
Fly 324 QPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGME----------------- 371
Fly 372 FKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPL 436
Fly 437 --STSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQ-QQPLHQEQRNAPKRYSSLRRSQ 498
Fly 499 QEASQHLAEQQQQQMQQQLHL-----QQQQQQQQSQIMIQDP-----HVLMQIAYQQQELQAQLQ 553
Fly 554 TMQLGPPTAAGAVPTP---------PKPHAPPAAAYPQAQAAPYYVTGTEPVPV------PVPQ- 602
Fly 603 --------APYV----NPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQ-PAQPYQNY 654
Fly 655 NTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGA 700 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| btz | NP_001263028.1 | DUF3597 | 2..>43 | CDD:289008 | 1/1 (100%) |
| Btz | 102..243 | CDD:214991 | 46/150 (31%) | ||
| CASC3 | NP_031385.2 | Btz | 146..248 | CDD:214991 | 44/142 (31%) |
| speckle localizer and RNA binding (SELOR) module | 170..245 | 38/113 (34%) | |||
| Nuclear localization signal 2. /evidence=ECO:0000255 | 254..262 | 3/7 (43%) | |||
| Necessary for localization in cytoplasmic stress granules | 377..703 | 85/391 (22%) | |||
| Nuclear export signal | 462..466 | 2/3 (67%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 492..538 | 6/57 (11%) | |||
| PHA03247 | <555..703 | CDD:223021 | 50/170 (29%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 633..703 | 29/92 (32%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165155354 | |
| Domainoid | 1 | 1.000 | 67 | 1.000 | Domainoid score | I9897 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4264 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 126 | 1.000 | Inparanoid score | I4710 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG47723 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0005383 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91060 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | LDO | PTHR13434 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3188 |
| SonicParanoid | 1 | 1.000 | - | - | X4312 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 11.020 | |||||