Protein Alignment btz and casc-3

DIOPT Version :10

• Sequence 1: NP_001263028.1
• Gene: btz / 43331
• FlyBaseID: FBgn0045862
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_493346.1
• Gene: casc-3 / 173203
• WormBaseID: WBGene00012343
• Length: 584
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 150/683 - (21%)
• Similarity: 213/683 - (31%)
• Gaps: 238/683 - (34%)

  Fly    29 VAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEES 93
            :|.......||:.......|.|...|....:...::|...|..|| |||.:.:...||..|||:
 Worm     1 MAAESATTETVEKSGNEESTVEVKVNGEAQNPPQESAKPAESVED-DDEPAPAKKRSGGDSEEK- 63

  Fly    94 ETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEI 158
              :||..|.|.|  |||.:..:|.           |::..||.||||.|.||.|||..
 Worm    64 --EDEAAEDGPE--DGEEKSNLDD-----------DQNVENPAYIPKTGRFYMHDDNR------- 106

  Fly   159 LIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGD-RWSHDRFEATE 222
                           .|::|            ..|:.......|:....|..| .|.||||:...
 Worm   107 ---------------RGDVN------------NSQVQDDDSDDRRNLKKSRADCDWKHDRFDEKF 144

  Fly   223 QAPKSRAELLQTYGYDIRNEDAPP--------------------------RARRRRRY---TRG- 257
            |.||::.:::..||:|||::|..|                          |.::.||.   |||
 Worm   145 QRPKTKKQIVTKYGFDIRHKDGTPIQDGEEIDAPAPESTEEESSDARQVSRQQKDRRVSSTTRGK 209

  Fly   258 ---------PSKYSRNWEDEQAYLKASNKERKPPRP--------QDFPALNERKPRGPRTSSSRE 305
                     |.| .|..||.....|...:|.:..||        |:.|  .::||..|.:|...|
 Worm   210 VGKSGTSRRPMK-QREREDTVDESKGEEEEDQGVRPAQKRQVKQQEKP--RKQKPAAPPSSEENE 271

  Fly   306 EKEN-------------------------------------RRSVAAEGLVPEKQQPLASSSN-- 331
            |.|:                                     |||..|.......::|:.|||.
 Worm   272 EDEDDGAIRRGQRRAVPLRRGTTSGPPSRLRGRMSHPMGPPRRSSGAPPSSASNRRPVESSSRGP 336

  Fly   332 ---PHRSQERERERERERERDREPKNR------------NFGRMNGGPGRQNGME---------- 371
               |..|..|:...:.:|..||...:|            ...|..||.||...:.
 Worm   337 PPPPSSSSRRDYSHQGDRNDDRFENHRRGVIRGASRGGGTVTRGTGGYGRTGAIRGGVRGSGAPR 401

  Fly   372 --FKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQT 434
              .::.:..:|....:||....|.     |:||.|.|....    :|......|..|.|..|...
 Worm   402 YGVRRTDTSEQSEGYQRGGSGTDY-----SSPRPNHQSDRS----YQASSTNFRGGSHPHPSANV 457

  Fly   435 -PLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQR------------- 485
             |.|....|........|....:.|            .||.......||::|
 Worm   458 YPSSRGGYSSNNADYASRGGGGYHG------------PPQHHNNHHNHQQKRFVQGPPPPMVAVG 510

  Fly   486 ----NAPKRYSSLRRSQQEASQHL-----AEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQI 541
                |........|.|....:||.     ....||::           :|.:.::..||
 Worm   511 VVPGNVVPPPQMTRGSTHGGNQHNGGGGGGSGGQQRI-----------RQPTDVVYFDP------ 558

  Fly   542 AYQQQELQAQLQTMQLGPPTAAGAVP-TPPKPH 573
              |||:...||      ||.:...:| ..||.|
 Worm   559 --QQQQGTRQL------PPRSKKVIPIVDPKDH 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btz	NP_001263028.1	Btz	102..243	CDD:214991	38/141 (27%)
casc-3	NP_493346.1	Btz	55..165	CDD:214991	46/159 (29%)