DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ALiX and AT1G13310

DIOPT Version :9

Sequence 1:	NP_651582.1	Gene:	ALiX / 43330	FlyBaseID:	FBgn0086346	Length:	836	Species:	Drosophila melanogaster
Sequence 2:	NP_563927.3	Gene:	AT1G13310 / 837891	AraportID:	AT1G13310	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	400	Identity:	79/400 - (19%)
Similarity:	153/400 - (38%)	Gaps:	98/400 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKFLGVPLKKPSEVDVIKPLNNLIQSTYNGAS-----------------EEEKGKYGEAVNEFS 48
            |.::| :|..|..|:        |.:.|...|.                 ||...|..:.::..:
plant     3 MMQYL-IPEPKTKEI--------LYEKTLQAAGPITLGEVKELTSKRKIIEESVNKTSKVIDSTT 58

  Fly    49 KQRNTAIWKFFE-------KYEASLEIVYAYYDQICALETKISVSELQIPFKWKDAFDKGSIFGG 106
            ::....:....|       :|...|..:..|.|:|      ..||.|:|  :|.         .|
plant    59 REMTRGLTSACEQDLHKLGEYLPLLFNLVHYTDKI------KRVSNLKI--RWS---------SG 106

  Fly   107 KISLTHTSLLYEKVC---------------VLFNIAALQSNIAANQSLDSDDGLKLTIKLLQQSA 156
            .||.|    |.::.|               ||| |.|::....|.:.:.:|.  |..:.:.::::
plant   107 LISQT----LIQRTCPKFFQVDNIMFEFGMVLF-IYAVKLRERAMELVSTDS--KKAVAVYREAS 164

  Fly   157 GIFQYLK----GATPAAVPSEPTPDLSQDTLTVLQALMVAQAQEVFILKAIKDNLKDQIIAKLCC 217
            |:|.:|.    ......:|....|:|:....:.|..|.:|:.|.|...||.:......:::||..
plant   165 GVFHHLSHEILPLLQTCLPPGKLPELTPPLCSALSLLCLAEGQAVTTEKAEESGKSASLLSKLHF 229

  Fly   218 Q----AEESYADVLRAMQKE----SVRSLWEKEWIPTIAGKQAGFHAL-TQLYQSLVCRAAKKIG 273
            .    ..|:||.:...:..|    |.|.|   |::.|:    ...|.| :|.|.:.:..:..::|
plant   230 GIFQFLSEAYALLSSRLTGEYKDLSTRFL---EYVTTM----GALHELKSQKYLAELLESEDRVG 287

  Fly   274 EEIARLRNAIDLFKAAQTRSGNETYLDEYFSRAK----RNLTESTKDNEFIYNEIIPELSTLTSP 334
            :.:..||.|:...|.: |.|.::.:: ..|.:.:    :|:.:..|.|:.:..:.||....:..|
plant   288 DAVGVLRRALAAAKKS-TPSKDDKWI-AIFKKEREDVAKNMAKYEKLNDSMMLQKIPIDREIPFP 350

  Fly   335 GKAQLAKPLP 344
            ...::...:|
plant   351 KGEKIVNLIP 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ALiX	NP_651582.1	BRO1_Alix	2..347	CDD:185763	77/398 (19%)
		V_Alix	362..698	CDD:185748
		ALIX_LYPXL_bnd	415..701	CDD:290660
		MFMR	733..822	CDD:285072
AT1G13310	NP_563927.3	BRO1_Alix_like_2	6..363	CDD:185770	77/396 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910