Protein Alignment ALiX and Rhpn1

DIOPT Version :10

• Sequence 1: NP_651582.1
• Gene: ALiX / 43330
• FlyBaseID: FBgn0086346
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_006241962.1
• Gene: Rhpn1 / 300030
• RGDID: 1305688
• Length: 662
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 120/466 - (25%)
• Similarity: 188/466 - (40%)
• Gaps: 72/466 - (15%)

  Fly     9 LKKPSEVDVIKPLNNLIQSTYNGASEEEKGKYGEAVNEFSKQRNTAIWKFFEKYEASLEIVYAYY 73
            ||:..|:|...||..||...:.    |:...|...:.|....|...  :...:.|..|:::.|||
  Rat   121 LKETKELDWATPLKELISEHFG----EDGASYETEIQELEDLRQAT--RTPSRDEVGLDLLAAYY 179

  Fly    74 DQICALETKISVSELQIP---FKWKDAFDKGSIFGGKISLTHTSLLYEKVCVLFNIAALQSNIAA 135
            .|:|.|:.:. .|..:.|   |.|.|     |:.|  :.....:|.:||..|||||.||.:.|.|
  Rat   180 SQLCFLDARF-FSPARSPGLLFHWYD-----SLTG--VPAQQRALAFEKGSVLFNIGALHTQIGA 236

  Fly   136 NQSLDSDDGLKLTIKLLQQSAGIFQYLKGATPAAVPSEPTPDLSQDTLTVLQALMVAQAQEVFI- 199
            .|.....:|.....:..|::||.|:.|:.....|    |:||:|..:|::|:.||||||||...
  Rat   237 RQDCSCTEGTSQAAEAFQRAAGAFRLLRENFSHA----PSPDMSAASLSMLEQLMVAQAQECIFR 297

  Fly   200 -----LKAIKDNLKDQI-IAKLCCQAEESYADVLRAMQKESVRSLWEKEWIPTIAGKQAGFHALT 258
                 ..|..|...||: :|:...|....|..|.|||.:..||......|......|...|.||.
  Rat   298 GLLLRASATPDICPDQLQLAQEATQVATEYGLVHRAMAQPPVRDYLPASWTNLARVKAEHFCALA 362

  Fly   259 QLYQSL-VCRAAKKIGEEIARLRNAIDLFKAAQTRSGNETYLDEYFSRAKRNLTESTKDNEFIYN 322
            ..:.:: :|.:......|::|..   |:|:.:.|.......|.:: ...:|.|.::......:..
  Rat   363 HYHAAMALCESTSAAKGELSRQE---DIFQPSATCEPQGPTLPQH-PEERRKLAKAHLKRAILGQ 423

  Fly   323 EIIPELSTLTS-PGKAQLAKPLPIAVPLAENFKDIFSSLVPVELHRALTA-SDMRRNEIVNVEIM 385
            |....|.||.. |.|.                 |:...:|...|.|:||. |::.|.:    :..
  Rat   424 EEALRLHTLCRVPRKV-----------------DLLQVVVTQALRRSLTKYSELERED----DFF 467

  Fly   386 KLREA----TQTLNAVLASLNLPAAVETADGNSGLPP----SLKEK------ANEVRQKGGIENV 436
            :..||    .:|..|...|:...:.|:..|....|.|    |.|.:      .:..|.:||..
  Rat   468 EAMEAPDIQPKTHQAPEVSIPSLSQVKVTDFFHRLGPLSVFSTKNRWQLVGPVHMTRGEGGFG-- 530

  Fly   437 QTMLKDLPELL 447
            .|:..|.|.|:
  Rat   531 FTLRGDSPVLI 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALiX	NP_651582.1	BRO1_Alix	2..347	CDD:185763	94/349 (27%)
		V_Alix	362..698	CDD:185748	24/101 (24%)
		PHA03247	<710..830	CDD:223021
Rhpn1	XP_006241962.1	HR1	28..112	CDD:469609
		BRO1_Rhophilin_1	116..499	CDD:185771	109/420 (26%)
		PDZ_rhophilin-like	519..594	CDD:467196	7/25 (28%)