| Sequence 1: | NP_651582.1 | Gene: | ALiX / 43330 | FlyBaseID: | FBgn0086346 | Length: | 836 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056281.1 | Gene: | PTPN23 / 25930 | HGNCID: | 14406 | Length: | 1636 | Species: | Homo sapiens |
| Alignment Length: | 863 | Identity: | 221/863 - (25%) |
|---|---|---|---|
| Similarity: | 377/863 - (43%) | Gaps: | 125/863 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 38 GKYGEAVN------EFSKQRNTAIWKFFEKYEASLEIVYAYYDQICALETKI---SVSELQIPFK 93
Fly 94 WKDAFDKGSIFGGKISLTHTSLLYEKVCVLFNIAALQSNIAANQSLDSDDGLKLTIKLLQQSAGI 158
Fly 159 FQYLKGATPAAVPSEPTPDLSQDTLTVLQALMVAQAQEVFILKAIKDNLKDQIIAKLCCQAEESY 223
Fly 224 ADVLRAMQKESVRSLW---EKEWIPTIAGKQAGFHALTQLYQSLVCRAAKKIGEEIARLRNAID- 284
Fly 285 LFKAAQTRSGN-ETYLDEY----------FSRAKRNLTESTKDNEFIYNEIIPELSTLTSPGKAQ 338
Fly 339 LAKPLPI-AVPLAENFKDIFSSLVPVELHRALTASDMRRNEIVNVEIMKLREATQTLNAVLASLN 402
Fly 403 L-PAAVETADGNSGLPPSLKEKA-------NEVRQ--------KGGIENVQTMLKDLPELLNRNR 451
Fly 452 EILDETERLLDEERDSDNQLRAQFKDRWTRISSDKLTEMFRTNAKKYREVITNAIEADKVVRQKF 516
Fly 517 EANQKGIQLLSLPPDQIQQSLPSASGSVDPNCSSV-QRLKKLMDDVETIKAEREAIESELKGATF 580
Fly 581 NMKDEFLIALQKDGAIDEPAL---SLARIGQVLNPLQQQVRESVERQQSLVSEIQSAHGAFVSET 642
Fly 643 GSCGSSRDTLYQELATAFDSYIELSGNLQEGTKFYNDLTQLLVVFQNKISDFVFARKTEKEELL- 706
Fly 707 KDLTTESSRQACPATPALPSHYASTSGSGSDIPPGSAPSVPP------------AASTANIPYPA 759
Fly 760 QVQGMPIPYGAQPGVPYPAYVPAPMP--------QSFNPYATLPYPGNYQYQGFPQGPPPGHYGT 816
Fly 817 YPG-SYANQQGGYPNQKP 833 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ALiX | NP_651582.1 | BRO1_Alix | 2..347 | CDD:185763 | 98/333 (29%) |
| V_Alix | 362..698 | CDD:185748 | 79/355 (22%) | ||
| ALIX_LYPXL_bnd | 415..701 | CDD:290660 | 70/304 (23%) | ||
| MFMR | 733..822 | CDD:285072 | 25/109 (23%) | ||
| PTPN23 | NP_056281.1 | BRO1_HD-PTP_like | 2..357 | CDD:185762 | 100/343 (29%) |
| TPR 1 | 250..283 | 9/32 (28%) | |||
| V_HD-PTP_like | 362..700 | CDD:185747 | 79/355 (22%) | ||
| TPR 2 | 374..407 | 5/32 (16%) | |||
| ALIX_LYPXL_bnd | 417..701 | CDD:290660 | 69/301 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 701..812 | 27/125 (22%) | |||
| His | 770..1130 | 22/87 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 888..1151 | ||||
| 6 X 2 AA approximate tandem repeats of P-Q | 953..964 | ||||
| Y_phosphatase | 1220..1450 | CDD:278528 | |||
| PTPc | 1220..1449 | CDD:238006 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1513..1636 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2220 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D498845at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R147 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.850 | |||||