Protein Alignment HSPBAP1 and HSPBAP1

DIOPT Version :10

• Sequence 1: NP_651581.2
• Gene: HSPBAP1 / 43329
• FlyBaseID: FBgn0263025
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_078886.2
• Gene: HSPBAP1 / 79663
• HGNCID: 16389
• Length: 488
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 96/305 - (31%)
• Similarity: 142/305 - (46%)
• Gaps: 47/305 - (15%)

  Fly     6 KLRDLILNTHVPLVLEQFPLKWECFEGSLHDWCKRF------DKEATCLPAFELMALADSSTPQW 64
            |.:::|::...|.:.......|..     ..|..::      .|:.    .|.:...:.|:.||:
Human    32 KAKEIIMSLQQPAIFCNMVFDWPA-----RHWNAKYLSQVLHGKQI----RFRMGMKSMSTVPQF 87

  Fly    65 ERKRTKSSQLLNMQQFL-------------RKYGVLDGDSTHWAAYQYKK-----ADEVPLSCRS 111
            |  .|.:.....:::||             |.|    ..|..||...||.     .|:..|.  .
Human    88 E--TTCNYVEATLEEFLTWNCDQSSISGPFRDY----DHSKFWAYADYKYFVSLFEDKTDLF--Q 144

  Fly   112 GIGFSSFGFPD-IGNDYRFWLGSEQANTPCHYDTFGVNIVVQVHGCKSWLLFPPE-TP-LQSTRI 173
            .:.:|.||||. .|.:...|:||..|:||||.|::|.|:|.||.|.|.|.||||| || |..|||
Human   145 DVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRI 209

  Fly   174 PYEETSVYCLENFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRHWWHYVEA-KSTSLSVNYW 237
            ||||:||:...|...||..:...:....|.|  ..|.||.||.||||||||||: ...::|:|.|
Human   210 PYEESSVFSKINVVNPDLKRFPQFRKAQRHA--VTLSPGQVLFVPRHWWHYVESIDPVTVSINSW 272

  Fly   238 VPLKVDMDLILDEFLVMHIVESFVRGESNQVKQYLLNPNQLDNVS 282
            :.|:.|....::|.:...:|.:....|:.|..:..|||.:::..|
Human   273 IELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETS 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	Cupin_8	<76..237	CDD:463936	73/182 (40%)
HSPBAP1	NP_078886.2	Cupin_8	37..272	CDD:463936	87/262 (33%)
		Interaction with HSPB1. /evidence=ECO:0000250	88..208		55/140 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..415