DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HSPBAP1 and Hspbap1

DIOPT Version :9

Sequence 1:	NP_651581.2	Gene:	HSPBAP1 / 43329	FlyBaseID:	FBgn0263025	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_006522532.1	Gene:	Hspbap1 / 66667	MGIID:	1913917	Length:	507	Species:	Mus musculus

Alignment Length:	323	Identity:	98/323 - (30%)
Similarity:	141/323 - (43%)	Gaps:	59/323 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KLRDLILNTHVPLVLEQFPLKWECFEGSLHDWCKRFDKEATCLPAFELMALADSST-PQWERKRT 69
            |.:::|::...|.:.......|.    |.|...|...|..........|.|..:.| ||:|   |
Mouse    32 KAKEIIMSLQQPAIFCNMVFDWP----SRHWTAKHLSKVLEGKQIRFRMGLRGTGTVPQYE---T 89

  Fly    70 KSSQL-LNMQQFLR---KYGVLDG---DSTH---WAAYQYK--------KADEVPLSCRSGIGFS 116
            :.|.: ..:::||.   ....:.|   |..|   ||...||        |.|..    :..:.:|
Mouse    90 ECSYVDATLEEFLTWNCDQSSISGPFKDYEHSKFWAYADYKYFVTLFEDKTDVF----QQEVVWS 150

  Fly   117 SFGFPD-IGNDYRFWLGSEQANTPCHYDTFGVNIVVQ-----------------VHGC------K 157
            .||||. .|.:...|:||..|:||||.|::|.|:|.|                 |..|      |
Mouse   151 DFGFPGRNGQESTLWIGSFGAHTPCHLDSYGCNLVFQRTEKFVETQRLHCGPLDVDRCQEAWIRK 215

  Fly   158 SWLLFPPE-TP-LQSTRIPYEETSVYCLENFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRH 220
            .|.||||| || |..|||||||:||:...|...||......::...|  :...|.||.||.||||
Mouse   216 RWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKCFPQFQKARR--HMVTLSPGQVLFVPRH 278

  Fly   221 WWHYVEA-KSTSLSVNYWVPLKVDMDLILDEFLVMHIVESFVRGESNQVKQYLLNPNQLDNVS 282
            ||||||: ...::|:|.|:.|:.|....::|.:...:|.:....|.....:..|||.:::..|
Mouse   279 WWHYVESLDPVTVSINSWIELEEDHLARVEEAITRMLVCTLKTAEDPHHPRTWLNPTEVEETS 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	cupin_like	11..237	CDD:304367	87/271 (32%)
Hspbap1	XP_006522532.1	Cupin_8	37..296	CDD:372651	87/271 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834609
Domainoid	1	1.000	116	1.000	Domainoid score	I5996
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	1	1.000	-	-		FOG0008275
OrthoInspector	1	1.000	-	-		oto92533
orthoMCL	1	0.900	-	-		OOG6_109247
Panther	1	1.100	-	-	LDO	PTHR12461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6086
SonicParanoid	1	1.000	-	-		X6251
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880