Protein Alignment HSPBAP1 and HIF1AN

DIOPT Version :9

• Sequence 1: NP_651581.2
• Gene: HSPBAP1 / 43329
• FlyBaseID: FBgn0263025
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: XP_011538242.1
• Gene: HIF1AN / 55662
• HGNCID: 17113
• Length: 369
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 66/326 - (20%)
• Similarity: 117/326 - (35%)
• Gaps: 114/326 - (34%)

  Fly    17 PLVLEQ----FP-LKWE--------------CFEGSLHDWCKRFDKEATCLPAFELMALADSSTP 62
            |:||..    :| |||:              .:..|.|.:....:|:         ||...:..|
Human    81 PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKK---------MANFQNFKP 136

  Fly    63 QWERKRTKSSQLLNMQQFLRKYG-------------------VLD--GDSTHWAAYQYKKADEVP 106
            :..|:..|..:.:...|.:::.|                   |:|  |.:.:|...|..|
Human   137 RSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGK----- 196

  Fly   107 LSCRSGIGFSSFGFPDIGNDYRFW---------LGSEQANTPCHYDTFGVNIVVQVHGCKSWLLF 162
                                 |.|         :|.|...||.|||. ..|...|:.|.|..:||
Human   197 ---------------------RGWGQLTSNLLLIGMEGNVTPAHYDE-QQNFFAQIKGYKRCILF 239

  Fly   163 PPET-------PLQSTRIPYEETSVYCLENFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRH 220
            ||:.       |:..   |.:..|....:|   ||..:..:::::  ..|...:.||:||.:|.:
Human   240 PPDQFECLYPYPVHH---PCDRQSQVDFDN---PDYERFPNFQNV--VGYETVVGPGDVLYIPMY 296

  Fly   221 WWHYVEA---KSTSLSVNYW-----VPLKVDMDLILDEFLVMHIVESFVRGESNQVKQYLLNPNQ 277
            |||::|:   ...:::||:|     .|.:::..      |..|...:.:|.....:.:.|.||.:
Human   297 WWHHIESLLNGGITITVNFWYKGAPTPKRIEYP------LKAHQKVAIMRNIEKMLGEALGNPQE 355

  Fly   278 L 278
            :
Human   356 V 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	cupin_like	11..237	CDD:304367	58/278 (21%)
HIF1AN	XP_011538242.1	Cupin_8	80..317	CDD:290351	58/279 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820