DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HSPBAP1 and hspbap1

DIOPT Version :9

Sequence 1:	NP_651581.2	Gene:	HSPBAP1 / 43329	FlyBaseID:	FBgn0263025	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_005167885.1	Gene:	hspbap1 / 445320	ZFINID:	ZDB-GENE-040808-38	Length:	456	Species:	Danio rerio

Alignment Length:	316	Identity:	102/316 - (32%)
Similarity:	150/316 - (47%)	Gaps:	46/316 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSSK------LRDLILNTHVPLVLEQFPLKWECFEGSLHDWCKRFDKEATCLP---AFELMALAD 58
            :|||      .|.::.....|.|.......|.    :|| |  ..:..:.||.   .|.:...::
Zfish     8 MSSKPFTPEEARRIVQVLQKPAVFLNMTTDWP----ALH-W--TVEHLSACLTKRIRFRVGKRSE 65

  Fly    59 SSTPQWERKRTKSSQL-LNMQQFLRKYGVLDGD-----------STHWAAYQYKKADEV----PL 107
            ...|.:|   |:.|.: ..:::|| .:...||:           ...||...||...::    |.
Zfish    66 DMAPLFE---TECSYVEATIKEFL-SWTANDGEPLVGPFLDYHCKEFWAYADYKYIAQLFQDKPA 126

  Fly   108 SCRSGIGFSSFGFPD-IGNDYRFWLGSEQANTPCHYDTFGVNIVVQVHGCKSWLLFPPETP--LQ 169
            ..:. :.:|.||||. .|.|...|:|::.||||||.|::|.|:|.|:.|.|.|.||||:..  |.
Zfish   127 MFQD-VVWSDFGFPGRDGRDSTLWIGTQCANTPCHLDSYGCNLVFQIQGRKRWHLFPPDDTACLY 190

  Fly   170 STRIPYEETSVYCLENFYAPDPAKISSYEHLGR-QAYHCNLQPGNVLIVPRHWWHYVEA-KSTSL 232
            .||:||||:||:...|...||..|..:|   || :.|...||||.||.||||||||||: ...::
Zfish   191 PTRVPYEESSVFSHVNVIRPDLKKFPAY---GRARLYTVTLQPGQVLFVPRHWWHYVESVDPVTV 252

  Fly   233 SVNYWVPLKVDMDLILDEFLVMHIVESFVRGESNQVKQYLLNPNQLDNVSTKPSDL 288
            |||.|:.:.:|.:..:.|.|...||.:.....|.......|||.: |.||:...::
Zfish   253 SVNSWIEMDMDDEARVAEALTKTIVCAVKSSPSLDNSDQWLNPTE-DGVSSHDENM 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	cupin_like	11..237	CDD:304367	85/249 (34%)
hspbap1	XP_005167885.1	Cupin_8	16..264	CDD:290351	87/262 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577595
Domainoid	1	1.000	124	1.000	Domainoid score	I5499
eggNOG	1	0.900	-	-		E1_KOG2132
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	1	1.000	-	-		FOG0008275
OrthoInspector	1	1.000	-	-		oto41078
orthoMCL	1	0.900	-	-		OOG6_109247
Panther	1	1.100	-	-	LDO	PTHR12461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6086
SonicParanoid	1	1.000	-	-		X6251
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.740