DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HSPBAP1 and jmjd-5

DIOPT Version :9

Sequence 1:	NP_651581.2	Gene:	HSPBAP1 / 43329	FlyBaseID:	FBgn0263025	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_505831.1	Gene:	jmjd-5 / 179543	WormBaseID:	WBGene00007387	Length:	578	Species:	Caenorhabditis elegans

Alignment Length:	191	Identity:	48/191 - (25%)
Similarity:	85/191 - (44%)	Gaps:	38/191 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 STPQWERKRTKSSQLLNMQQFLRKYGVLDGDSTHWAAYQYKKADEVPLSCRSGIGFSSFGFPDI- 123
            |...|.:|      |:..::|:|     :.::......|::..|:||...|..|      .||:
Worm   411 SDENWSQK------LMTFKEFIR-----NSENERLYLAQHRLFDQVPHLKRDVI------IPDVC 458

  Fly   124 --------GNDYRFWLGSEQANTPCHYDTFGVNIVVQVHGCKSWLLFPPETPLQSTRIPYE---- 176
                    ..|...|:|.:...:|.|.|. ..|:.|||||.|.:.:..||:  ..:..|::
Worm   459 FGESSNPENVDMNMWIGPQDTVSPLHTDP-RKNMFVQVHGTKLFRMVAPES--SESVYPFDGILS 520

  Fly   177 ETSVYCLENFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRHWWHYVEAKSTSLSVNYW 237
            .||...:||   ||.....::|.:  :.....:.||:.:.:|..|||:|.:.|.|:|:::|
Worm   521 NTSQVDVEN---PDLKIFPNFEQV--EVLDAVINPGDAIFIPEKWWHFVRSTSPSISISFW 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	cupin_like	11..237	CDD:304367	47/189 (25%)
jmjd-5	NP_505831.1	NAT_SF	26..137	CDD:388411
jmjd-5	NP_505831.1	Cupin_8	360..578	CDD:372651	48/191 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810