DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HSPBAP1 and kdm8

DIOPT Version :9

Sequence 1:	NP_651581.2	Gene:	HSPBAP1 / 43329	FlyBaseID:	FBgn0263025	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001121525.1	Gene:	kdm8 / 100158649	XenbaseID:	XB-GENE-5811534	Length:	443	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	66/248 - (26%)
Similarity:	100/248 - (40%)	Gaps:	47/248 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RDLILNTHVPLVLEQFPLKWECFEGSLHDWCKRF-DKEATC--LPAFELMALADSST-PQWERKR 68
            ||..|....|:|||.....|.|    |..|...: .:.|.|  :|    :.|....| .:|
Frog   223 RDHYLVPQKPVVLEGVIDHWPC----LKKWSVEYIQRVAGCRTVP----VELGSRYTDAEW---- 275

  Fly    69 TKSSQLLNMQQFLRKYGVLDGDSTHWAAYQYKKADEVPLSCRSGIGFSSFGFPD---IGN----- 125
              |.:|:.:.:|:.|| :||..:......|::..:::| ..:..|     ..||   :|.
Frog   276 --SQRLMTVNEFITKY-ILDKQNGIGYLAQHQLFEQIP-ELKEDI-----CIPDYCCLGEASEDE 331

  Fly   126 -DYRFWLGSEQANTPCHYDTFGVNIVVQVHGCKSWLLFP-PET----PLQSTRIPYEETSVYCLE 184
             ....|.|.....:|.|.|. ..|.:.|:.|.|...::. .||    |..|:.:  ..||...:|
Frog   332 ITINAWFGPAGTVSPLHQDP-QQNFLAQIVGRKYIRVYSVAETEKLYPFDSSIL--HNTSQVDVE 393

  Fly   185 NFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRHWWHYVEAKSTSLSVNYW 237
               :||..|...:.....|  .|.|.||.||.:|..||||:.|...|.||::|
Frog   394 ---SPDQNKFPRFSQASYQ--ECILSPGQVLFIPVKWWHYIRALDLSFSVSFW 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HSPBAP1	NP_651581.2	cupin_like	11..237	CDD:304367	63/243 (26%)
kdm8	NP_001121525.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..174
kdm8	NP_001121525.1	Cupin_8	222..443	CDD:372651	66/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920