Protein Alignment Sce and PCGF3

DIOPT Version :9

• Sequence 1: NP_477509.1
• Gene: Sce / 43327
• FlyBaseID: FBgn0003330
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001304765.1
• Gene: PCGF3 / 10336
• HGNCID: 10066
• Length: 242
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 72/392 - (18%)
• Similarity: 119/392 - (30%)
• Gaps: 168/392 - (42%)

  Fly    40 LHSELMCPICLDMLKKTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRADPNFDLL 104
            :::.:.|.:|...|....|..||||.||..|:|..|.. |..|||||                ::
Human    11 INAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEE-NNTCPTCR----------------IV 58

  Fly   105 ISKIYPSREEYEAIQEKVMAKFNQTQSQQALVNSINEGIKLQSQNRPQRFRTKGGGGGGGGGGNG 169
            |.:.:|            :......::.|.:|..:..|::.....:.:.|..|.|
Human    59 IHQSHP------------LQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLG---------- 101

  Fly   170 NGAANVAAPPAPGAPTAVGRNASNQMHVHDTASNDSNSNTNSIDRENRDPGHSGTSAASAITSAS 234
                    ...||  ...|...|.:.|:      ||:.|..:
Human   102 --------MEVPG--DIKGETCSAKQHL------DSHRNGET----------------------- 127

  Fly   235 NAAPSSSANSGASTSATRMQVDDASNPPSVRSTPSPVPSNSSSSKPKRAMSVLTSERSEESESDS 299
                               :.||:||            ..::..||:        |.::...||.
Human   128 -------------------KADDSSN------------KEAAEEKPE--------EDNDYHRSDE 153

  Fly   300 QMDCRTEGDSNIDTEGEGNGELGINDEIELVFKPHPTEMSADNQLIRALKENCVRYIKTTANATV 364
            |:....|.:|:                                 .:|.||.   ::|:.:|.|||
Human   154 QVSICLECNSS---------------------------------KLRGLKR---KWIRCSAQATV 182

  Fly   365 DHLSKYLAMRLTLDLGADLPEACRVLNFCIYVAPQPQQLVILNGNQTLHQVNDKFWKVNK-PMEM 428
            .||.|::|.:|.|....:|...|..              .||..:.||..|....|:..| |:.:
Human   183 LHLKKFIAKKLNLSSFNELDILCNE--------------EILGKDHTLKFVVVTRWRFKKAPLLL 233

  Fly   429 YY 430
            :|
Human   234 HY 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sce	NP_477509.1	RING	45..89	CDD:238093	19/43 (44%)
		RAWUL	336..431	CDD:292824	25/96 (26%)
PCGF3	NP_001304765.1	RING-HC_PCGF3	14..60	CDD:319649	19/62 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	115..149		11/101 (11%)
		Interaction with BCORL1. /evidence=ECO:0000269|PubMed:27568929	132..242		35/174 (20%)
		RAWUL_PCGF3	154..236	CDD:340603	28/132 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910