DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5590 and SPS19

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_014197.2	Gene:	SPS19 / 855518	SGDID:	S000005146	Length:	292	Species:	Saccharomyces cerevisiae

Alignment Length:	246	Identity:	67/246 - (27%)
Similarity:	98/246 - (39%)	Gaps:	29/246 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GRTLFITGASRGIGKE-------IALKAA---RDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKA 63
            |:..|:||.:..|.:.       :..|||   ||......|||......|....:.:.|.
Yeast    24 GKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLAKDKDAVLAIAN----- 83

  Fly    64 GGKAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGT 128
                    ||||:.:||.:||:..|.|||.||.||..|:...:.:..:.....:..:.:|:..|:
Yeast    84 --------VDVRNFEQVENAVKKTVEKFGKIDFVIAGAAGNFVCDFANLSPNAFKSVVDIDLLGS 140

  Fly   129 FLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVN 193
            |..:|.||..||||. ..||.:|.........|..||.  .||.|:......:|.|....||..|
Yeast   141 FNTAKACLKELKKSK-GSILFVSATFHYYGVPFQGHVG--AAKAGIDALAKNLAVELGPLGIRSN 202

  Fly   194 ALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFF 244
            .:.|....:|..::.|.|   .|:..|............||:..:||...|
Yeast   203 CIAPGAIDNTEGLKRLAG---KKYKEKALAKIPLQRLGSTRDIAESTVYIF 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	67/246 (27%)
		PRK08278	7..277	CDD:181349	67/246 (27%)
		SCP2	317..406	CDD:280250
SPS19	NP_014197.2	TER_DECR_SDR_a	22..270	CDD:187627	67/246 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900