DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and OAR1

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_012868.1	Gene:	OAR1 / 853810	SGDID:	S000001538	Length:	278	Species:	Saccharomyces cerevisiae

Alignment Length:	276	Identity:	61/276 - (22%)
Similarity:	107/276 - (38%)	Gaps:	66/276 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAY--PCVVDV-- 74
            :|||:|||||.|..|..:.|.:.::...|.|...:      :|.:..:...|.:|  .|.:.:
Yeast     9 VTGATRGIGKAICQKLFQKGLSCIILGSTKESIER------TAIDRGQLQSGLSYQRQCAIAIDF 67

  Fly    75 ------------------RDE---QQVRSAVEAAVAKFGG------IDIVINNA----SAISLTN 108
                              :|.   :|..|.:.....|:..      ::::||.|    .::|:..
Yeast    68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRT 132

  Fly   109 TPDTDMKRYDLMHNINTRGTFLVSKVCLPYLKKSN-----------HAHILNISPPL-SMKPKWF 161
            |..   :..|:| |:|......::.:|:.|:.||.           ...|:|||..| |.|.|..
Yeast   133 TAS---QIQDIM-NVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVP 193

  Fly   162 GPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWPRTAIHTAAI--------EMLTGPDSAKWS 218
            |..| |:.:|..:|.....:|||.:...|....:.|.....|..|        |||.....|..:
Yeast   194 GTSV-YSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGT 257

  Fly   219 RKPEIMADAAYAILTR 234
            ..|..:|:..:::.:|
Yeast   258 SAPAEIAEEVWSLYSR 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	61/276 (22%)
		PRK08278	7..277	CDD:181349	61/276 (22%)
		SCP2	317..406	CDD:280250
OAR1	NP_012868.1	SDR_c	7..275	CDD:212491	61/276 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900