Protein Alignment CG5590 and Hsdl2

DIOPT Version :9

• Sequence 1: NP_651578.1
• Gene: CG5590 / 43325
• FlyBaseID: FBgn0039537
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_077217.2
• Gene: Hsdl2 / 72479
• MGIID: 1919729
• Length: 490
• Species: Mus musculus
• Alignment Length: 491
• Identity: 243/491 - (49%)
• Similarity: 298/491 - (60%)
• Gaps: 85/491 - (17%)

  Fly     3 NTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKA 67
            |||||||.|:|||||||||||.||||||:||||||:||||.:.||||.||||:||||||.|||.|
Mouse     4 NTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGTA 68

  Fly    68 YPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVS 132
            .|||||||||||:.||||.||.|||||||::|||||||||||.||..||.|||.|:|||||:|.|
Mouse    69 LPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYLTS 133

  Fly   133 KVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWP 197
            |.|:|:||||...||||:||||::.|.||..|.|||:|||||||||||||.||:.| |:||||||
Mouse   134 KACIPFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRGE-IAVNALWP 197

  Fly   198 RTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEYA 262
            ||||||||::||.|.......||.:|:|||||:|..| |:..||.|.:|:.:|:..||.:...||
Mouse   198 RTAIHTAAMDMLGGSGVENQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKNFDVYA 261

  Fly   263 CFRENADKLMVDFFVEEKGAPVENEAAAEDAAAPASGGDVKI----------------------- 304
            .  .....|:.|||::|....|..|..:.|:........:::
Mouse   262 I--APGHPLLPDFFLDEHPDAVMEEKESNDSVPEVKEEKLQLQEESQLQKQPQLQEQPQLQEKPQ 324

  Fly   305 ----------------------------PQL------------------------------FRKI 311
                                        |||                              ||.:
Mouse   325 LQEKPQLQEQPQLQEKPQLQEQPQQREQPQLQQQPRPRQQPQPFVQSMLPQKPHFGAVEETFRIV 389

  Fly   312 ESLLSPEIVSKTQAVFQFNISGAEQGTWFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSG 376
            :..||.|:|..||||:||.:||.:.||||||||:..|..|.|.|:...|..::|.:.:|..||||
Mouse   390 KDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATDDFVKMFSG 454

  Fly   377 KLKAAPAYMTGKLKISGDFQKALKLEKLMKALKSKL 412
            |||...|:|:|||||.|:...|:||||||..:.|:|
Mouse   455 KLKPTMAFMSGKLKIKGNIALAIKLEKLMTQMNSRL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	171/239 (72%)
		PRK08278	7..277	CDD:181349	178/269 (66%)
		SCP2	317..406	CDD:280250	46/88 (52%)
Hsdl2	NP_077217.2	HSDL2_SDR_c	8..248	CDD:187663	170/241 (71%)
		adh_short	12..197	CDD:278532	139/185 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..370		5/87 (6%)
		SCP2	390..483	CDD:280250	47/92 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836955
Domainoid	1	1.000	285	1.000	Domainoid score	I1605
eggNOG	1	0.900	-	-		E1_KOG4170
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	360	1.000	Inparanoid score	I2198
Isobase	1	0.950	-	0	Normalized mean entropy	S1809
OMA	1	1.010	-	-		QHG63699
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005600
OrthoInspector	1	1.000	-	-		oto95027
orthoMCL	1	0.900	-	-		OOG6_103987
Panther	1	1.100	-	-	LDO	PTHR42808
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5337
SonicParanoid	1	1.000	-	-		X4574
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.740