DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and SCP2

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_002970.2	Gene:	SCP2 / 6342	HGNCID:	10606	Length:	547	Species:	Homo sapiens

Alignment Length:	131	Identity:	44/131 - (33%)
Similarity:	67/131 - (51%)	Gaps:	14/131 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 EAAAE------DAAAPASGGD-VKIPQLFRKIESLLSPE---IVSKTQAVFQFNIS---GAEQGT 338
            |||:.      :|...:|..| .|...:|::||..|..|   .|.|...:|.|.:.   |.::.|
Human   409 EAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEAT 473

  Fly   339 WFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDFQKALKLEK 403
            |.:|:|||.||....:...| |.|:||...:|..:.:||:....|:..|||||:|:...|:||:.
Human   474 WVVDVKNGKGSVLPNSDKKA-DCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQN 537

  Fly   404 L 404
            |
Human   538 L 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959
		PRK08278	7..277	CDD:181349
		SCP2	317..406	CDD:280250	33/94 (35%)
SCP2	NP_002970.2	PRK08256	12..404	CDD:181327
		SCP2	452..538	CDD:307934	31/86 (36%)
		Microbody targeting signal. /evidence=ECO:0000255	545..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810