DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5590 and Dhrs1

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_081095.2	Gene:	Dhrs1 / 52585	MGIID:	1196314	Length:	313	Species:	Mus musculus

Alignment Length:	274	Identity:	63/274 - (22%)
Similarity:	118/274 - (43%)	Gaps:	33/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYPCV 71
            :.|:...:||||||||:.|||:..:.||.:.:..:..:       |:.:.|:|.:..||:..|.|
Mouse     5 MKGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLD-------TLRATAQEAQSLGGRCVPVV 62

  Fly    72 VDVRDEQQVRSAVEAA-VAKFGGIDIVINNASA-----ISLTNTP--DTDMKRYDLMHNINTRGT 128
            .|...|.:|:|..|.. ..:.|.:|:::|||.|     ::.||..  :.....:|.::|:..||.
Mouse    63 CDSSQESEVKSLFEQVDREQKGRLDVLVNNAYAGVQAILNTTNKSFWEVPASIWDDINNVGLRGH 127

  Fly   129 FLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVN 193
            :|.|......:..:....|:.:|.|..::..:   :|.|.:.|..........|.|.:..|:|..
Mouse   128 YLCSVYGARLMVPAGKGLIVIVSSPGGLQHMF---NVPYGVGKAACDRLAADCAHELRRHGVSYV 189

  Fly   194 ALWPRTAIHTAAIEMLTGPDSAK------------WSRKPEIMADAAYAILTREPR--QSTGQFF 244
            :|||.........|.:...|:.:            .:..||:......|:.| :|.  ..:|:..
Mouse   190 SLWPGLVQTEMVKEFMAKEDTPEDPLFKKMKPDFSSAESPEMSGKCVVALAT-DPNILNLSGKVL 253

  Fly   245 VDDEVLESAGITDL 258
            ...::....|:.|:
Mouse   254 PSCDLARRYGLKDI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	61/259 (24%)
		PRK08278	7..277	CDD:181349	63/274 (23%)
		SCP2	317..406	CDD:280250
Dhrs1	NP_081095.2	DHRS1-like_SDR_c	5..271	CDD:187664	63/274 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810