DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and zgc:101858

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001005597.1	Gene:	zgc:101858 / 449555	ZFINID:	ZDB-GENE-040927-13	Length:	265	Species:	Danio rerio

Alignment Length:	244	Identity:	70/244 - (28%)
Similarity:	121/244 - (49%)	Gaps:	33/244 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYP 69
            |.|..:...|||||.|||...||..|:.||.:.:..:..|       .:...|:|.| |.|.|.|
Zfish    10 GSLNDKVTLITGASSGIGAGTALLFAKLGARLALNGRDVE-------NLTKVAKECE-ACGAAKP 66

  Fly    70 CVV--DVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVS 132
            .:|  |:.||:.||..||..:|.||.:|:::|:|..:::.:...|||.:||.:.::|.|..:.::
Zfish    67 LLVAGDLTDEETVRRTVEEVIAHFGRLDVLVNSAGILAMGSIETTDMAQYDKVMSVNVRSIYHLT 131

  Fly   133 KVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWP 197
            .:|:|:|.|:. ..|:|:|.....:.  |...:||.|:|..:......:|.|...:.:.||::.|
Zfish   132 HLCVPHLIKTK-GSIVNVSSVNGQRS--FPGVLAYCMSKSAIDQFTRCVALELASKQVRVNSVCP 193

  Fly   198 R---TAIHTAAIEMLTGPDSAKWSR------------KPEIMADAAYAI 231
            .   |.:|..|     |.|..::::            :|..:.:.|:||
Zfish   194 GVIITEVHKRA-----GLDEEQYAQFIEKCKVTHALGRPGEVDEVAHAI 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	70/244 (29%)
		PRK08278	7..277	CDD:181349	69/242 (29%)
		SCP2	317..406	CDD:280250
zgc:101858	NP_001005597.1	fabG	11..260	CDD:235546	69/243 (28%)
zgc:101858	NP_001005597.1	SDR_c11	12..262	CDD:187622	69/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810