DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and CG31546

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_730973.1	Gene:	CG31546 / 40691	FlyBaseID:	FBgn0051546	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	69/316 - (21%)
Similarity:	116/316 - (36%)	Gaps:	75/316 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MINTGK----LAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIE 61
            |.:.||    .:|:.:.||||:.|||...|...::.||.:.:..:..|      |.| ...:...
  Fly     1 MGSKGKAGLDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEE------GLI-CVMKRCM 58

  Fly    62 KAGGKAYPCVVDVRDEQQVRSAVEAAVAKF-GGIDIVINNASAISLTNTPDTDMKRYDLMHNINT 125
            |.|.:.|....|:....::.........:: |.:|:::|.|..:.......|::..:..:...|.
  Fly    59 KMGHEPYGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANV 123

  Fly   126 RGTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGI 190
            |..|.::|:.||.|.:.. ..|:|:|....::.  |...|||.|:|..:......:|.:...:|:
  Fly   124 RSGFYLTKLLLPQLLQCK-GSIVNVSSVCGLRA--FPNLVAYNMSKAAVDQFTRSLALDLGPQGV 185

  Fly   191 SVNALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGI 255
            .|||:.|.                               .|.|.               |:.||.
  Fly   186 RVNAVNPG-------------------------------VIRTN---------------LQKAGG 204

  Fly   256 TDLTEYACFRENADKLMVDFFVEEKGAPVENEAA----AEDAAA-------PASGG 300
            .|...||.|.|::.|...   :...|.|.|..||    |.:.|:       |..||
  Fly   205 MDEQSYAEFLEHSKKTHA---LGRIGEPKEVAAAICFLASELASFVTGVTLPVDGG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	49/244 (20%)
		PRK08278	7..277	CDD:181349	56/270 (21%)
		SCP2	317..406	CDD:280250
CG31546	NP_730973.1	fabG	9..257	CDD:235975	64/306 (21%)
CG31546	NP_730973.1	NADB_Rossmann	11..261	CDD:304358	66/306 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830