DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5590 and dhrs1

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001002205.1	Gene:	dhrs1 / 368670	ZFINID:	ZDB-GENE-030616-591	Length:	310	Species:	Danio rerio

Alignment Length:	263	Identity:	68/263 - (25%)
Similarity:	113/263 - (42%)	Gaps:	29/263 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYPCV 71
            |:|....:||||||||:.|||:.:..||.:.:..:..:       ::...|.|:.:.||:..|.|
Zfish     3 LSGWICVVTGASRGIGRGIALQLSEAGATVYITGRQEK-------SLKQTAAEVAERGGRCLPVV 60

  Fly    72 VDVRDEQQVRSAVEAAVAKFGG-IDIVINNASA---ISLTNTP----DTDMKRYDLMHNINTRGT 128
            .|...|:.::...|....:..| :||::|||.|   ..|.|..    :.|...:|.::|...||.
Zfish    61 CDSSKEEDIKELFERVEREQNGRLDILVNNAYAGVQAILDNVSKKFWEVDPGIWDTINNTGLRGH 125

  Fly   129 FLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVN 193
            :..|......:.......|:.||   ||....:..:|.|.:.|.........|..|.|..|::..
Zfish   126 YFCSVYAARLMVAQGKGLIVVIS---SMGGLRYLFNVPYGVGKAACDRMAADMGIELKKRGVASV 187

  Fly   194 ALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYA-ILTR-EPRQSTGQFFVDDEVLESAGIT 256
            :||| .|:.|..|:.....|..    .|..  |:.|. :.|. |..:.:|:..|  |:.:..|:.
Zfish   188 SLWP-GAVQTETIKQYMSQDEG----PPGF--DSKYKDVFTNGETTELSGRCIV--ELAKDKGLM 243

  Fly   257 DLT 259
            .:|
Zfish   244 SMT 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	64/247 (26%)
		PRK08278	7..277	CDD:181349	68/263 (26%)
		SCP2	317..406	CDD:280250
dhrs1	NP_001002205.1	PRK08303	1..267	CDD:236229	68/263 (26%)
dhrs1	NP_001002205.1	DHRS1-like_SDR_c	3..268	CDD:187664	68/263 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810