DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and CG40486

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001036311.2	Gene:	CG40486 / 3355162	FlyBaseID:	FBgn0263830	Length:	247	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	49/216 - (22%)
Similarity:	89/216 - (41%)	Gaps:	54/216 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RTLFITGASRGIGKEIALKAARDGANIVVAAKTAE---------PHPKLPGTIYSAAEEIEKAGG 65
            |...:||||.|||..:|......|..:|..|:..:         | |:|.|.::
  Fly     7 RVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLP-PELQGRLH----------- 59

  Fly    66 KAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFL 130
             |..|  ||.|...|.:|.:....:.||.||::|||..::.......::::...:.|:|..|..:
  Fly    60 -AIHC--DVEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVI 121

  Fly   131 VSKVCLPYLKK---SNHAHILN-------ISPP------LSMKPKWFGPHVAYTMAKYGMSMCVL 179
            .::.....:::   ..|..::|       |:||      |:|          |.:.|:|::..:.
  Fly   122 CTRRAFRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNM----------YPLTKHGVTAMLE 176

  Fly   180 GMAAE---FKDEGISVNALWP 197
            .:..|   ||.: |.|.::.|
  Fly   177 VLRQELRGFKTK-IKVTSITP 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	49/216 (23%)
		PRK08278	7..277	CDD:181349	49/216 (23%)
		SCP2	317..406	CDD:280250
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	49/216 (23%)
CG40486	NP_001036311.2	NADB_Rossmann	1..242	CDD:304358	49/216 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435158
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930