Protein Alignment CG5590 and Hsdl2

DIOPT Version :9

• Sequence 1: NP_651578.1
• Gene: CG5590 / 43325
• FlyBaseID: FBgn0039537
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_001020868.1
• Gene: Hsdl2 / 313200
• RGDID: 1305387
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 243/525 - (46%)
• Similarity: 300/525 - (57%)
• Gaps: 119/525 - (22%)

  Fly     3 NTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKA 67
            |||||||.|:|||||||||||.||||||:||||||:||||.:.||||.||||:||||||.|||||
  Rat     4 NTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQRHPKLLGTIYTAAEEIEAAGGKA 68

  Fly    68 YPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVS 132
            .|||||||||||:.||||.||.:||||||::|||||||||||.:|..||.|||.::|||||:|.|
  Rat    69 LPCVVDVRDEQQINSAVEKAVERFGGIDILVNNASAISLTNTLETPTKRVDLMMSVNTRGTYLTS 133

  Fly   133 KVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWP 197
            |.|:|:||||..|||||:||||::.|.||..|.|||:|||||||||||||.||:.| |:||||||
  Rat   134 KACIPFLKKSKVAHILNLSPPLNLNPMWFKQHCAYTIAKYGMSMCVLGMAEEFRGE-IAVNALWP 197

  Fly   198 RTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEYA 262
            ||||||||::||.|.......||.:|:|||||:|..| |:..||.|.:|:.:|:..||.|...||
  Rat   198 RTAIHTAAMDMLGGAGVESQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKDFDIYA 261

  Fly   263 CFRENADKLMVDFFVEEKGAPVENEAAAEDAAAPASGGDVKI----------------------- 304
            .  .....|:.|||::|....|..|..:.|.........:::
  Rat   262 I--TPGHPLLPDFFLDEHPDAVMEEKESYDPVPEVKEEKLQLQEQPQLQEQPQLQEKPQLQEQPQ 324

  Fly   305 --------------------------------------PQL------------------------ 307
                                                  |||
  Rat   325 LQEKPQLQEQPQLQEQPQLQEQPQQQPQLQEQPQLQEKPQLQEQPQQQEKPQPQQQPQQQPQQRP 389

  Fly   308 ------------------------------FRKIESLLSPEIVSKTQAVFQFNISGAEQGTWFLD 342
                                          ||.::..||.|:|..||||:||.:||.:.||||||
  Rat   390 QQRPQPQPQPQPLLQSVLPPKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLD 454

  Fly   343 LKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDFQKALKLEKLMKA 407
            ||:..|..|.|.|:...|..::|.:::|..|||||||...|:|:|||||.|:...|:||||||..
  Rat   455 LKSKGGKVGHGEPSDRADVVMSMATEDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTH 519

  Fly   408 LKSKL 412
            :.|:|
  Rat   520 MNSRL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	170/239 (71%)
		PRK08278	7..277	CDD:181349	178/269 (66%)
		SCP2	317..406	CDD:280250	46/88 (52%)
Hsdl2	NP_001020868.1	HSDL2_SDR_c	8..248	CDD:187663	169/241 (70%)
		adh_short	12..197	CDD:278532	138/185 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..410		5/126 (4%)
		SCP2	424..517	CDD:280250	47/92 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340676
Domainoid	1	1.000	284	1.000	Domainoid score	I1558
eggNOG	1	0.900	-	-		E1_KOG4170
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H75204
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2130
OMA	1	1.010	-	-		QHG63699
OrthoDB	1	1.010	-	-		D1361949at2759
OrthoFinder	1	1.000	-	-		FOG0005600
OrthoInspector	1	1.000	-	-		oto98524
orthoMCL	1	0.900	-	-		OOG6_103987
Panther	1	1.100	-	-	LDO	PTHR42808
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4574
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770