DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and CG13377

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001259089.1	Gene:	CG13377 / 30972	FlyBaseID:	FBgn0261446	Length:	330	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	56/272 - (20%)
Similarity:	102/272 - (37%)	Gaps:	43/272 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEI-----EK 62
            |......|.:.||.|...:|.::....|..|..:....|.|:  ..||..:.....:|     |.
  Fly    39 NADSHPSRVVLITSADTALGLQLCTHLANKGYRVFAGMKEAQ--DSLPAKLLCGWMKIREYSEEP 101

  Fly    63 AGGKAYPCVVDVRDEQQVRSAVEAAVAKFG----GIDIVINNASAISLTNTPDTDMKRYDLMHNI 123
            ..|...|..:||..|..:|.|.....|...    ||..|||.:.::........::::::.|...
  Fly   102 IAGTIIPMRLDVTREDVLREATVIIGANLNADERGIAAVINTSGSVFRGQVESQNVQQWEHMLRT 166

  Fly   124 NTRGTFLVSKVCLPYLK--KSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFK 186
            |..||..|:|..:.:|:  :....::..:|...:.:.:..| .||:..::..:..|...:..|..
  Fly   167 NILGTLRVAKAFVCFLRPTRGRLLYLGGVSGGGNARNEGDG-LVAFNASRVAVDKCAEELRKELH 230

  Fly   187 DEGISVNAL----WPRTAIHTAAI----EMLTG-----------PDS------AKWSRKPEIMAD 226
            ..|:||.||    ....:::.|.:    .::.|           ||:      |.|...|:
  Fly   231 PYGVSVVALDTCGMTAESLYKAPVAQTMSLVVGAPTQYTADVLSPDALHVIERALWDYVPQ---- 291

  Fly   227 AAYAILTREPRQ 238
            ..||:|:....|
  Fly   292 QRYALLSHNKYQ 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	55/270 (20%)
		PRK08278	7..277	CDD:181349	55/268 (21%)
		SCP2	317..406	CDD:280250
CG13377	NP_001259089.1	adh_short	46..246	CDD:278532	44/202 (22%)
CG13377	NP_001259089.1	NADB_Rossmann	46..>237	CDD:304358	41/193 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930