DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001033027.2	Gene:	Dhrs4 / 28200	MGIID:	90169	Length:	279	Species:	Mus musculus

Alignment Length:	256	Identity:	62/256 - (24%)
Similarity:	108/256 - (42%)	Gaps:	56/256 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAG-----GK 66
            |:.:...:|.::.|||..||.:.|.|||::||:::..:...:...|:  ..|.:...|     ||
Mouse    31 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATL--QGEGLSVTGIVCHVGK 93

  Fly    67 AYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAIS--LTNTPDTDMKRYDLMHNINTRGTF 129
            |       .|.:::   :..|:.:..||||:::|| |::  ..|..|...:.:|.:.:||...|.
Mouse    94 A-------EDREKL---ITTALKRHQGIDILVSNA-AVNPFFGNLMDVTEEVWDKVLSINVTATA 147

  Fly   130 LVSKVCLPYLKKSNHAHILNIS--------PPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFK 186
            ::.|..:|.::|.....::.:.        |.|       ||   |.::|..:.......|||..
Mouse   148 MMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSL-------GP---YNVSKTALLGLTKNFAAELA 202

  Fly   187 DEGISVNALWP---RTAIHTAAIEMLTGPDSAKWSR------KPEIMA---------DAAY 229
            .:.|.||.|.|   :|...:...|.....|..|.:.      |||..|         ||:|
Mouse   203 PKNIRVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASY 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	62/256 (24%)
		PRK08278	7..277	CDD:181349	62/256 (24%)
		SCP2	317..406	CDD:280250
Dhrs4	NP_001033027.2	CR_SDR_c	24..279	CDD:187641	62/256 (24%)
		fabG	31..274	CDD:235975	62/256 (24%)
		Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900