DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_695227.2	Gene:	Dhrs4 / 266686	RGDID:	708482	Length:	279	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	51/206 - (24%)
Similarity:	93/206 - (45%)	Gaps:	38/206 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAG-----GK 66
            ||.:...:|.::.|||..||.:.|.|||::|::::..:...:...|:  ..|.:...|     ||
  Rat    31 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATL--QGEGLSVTGVVCHVGK 93

  Fly    67 AYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAIS--LTNTPDTDMKRYDLMHNINTRGTF 129
            |       .|.:::   |..|:....||||:::|| |::  ..|..|...:.::.:.:||...:.
  Rat    94 A-------EDREKL---VNMALKLHQGIDILVSNA-AVNPFFGNLMDVTEEVWNKVLSINVTASA 147

  Fly   130 LVSKVCLPYLKKSNHAHILNIS--------PPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFK 186
            ::.|..:|.::|.....::.:|        |.|       ||   |.::|..:.......|||..
  Rat   148 MMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSL-------GP---YNVSKTALLGLTKNFAAELA 202

  Fly   187 DEGISVNALWP 197
            .:.|.||.|.|
  Rat   203 PKNIRVNCLAP 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	51/206 (25%)
		PRK08278	7..277	CDD:181349	51/206 (25%)
		SCP2	317..406	CDD:280250
Dhrs4	NP_695227.2	CR_SDR_c	24..279	CDD:187641	51/206 (25%)
Dhrs4	NP_695227.2	Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900