DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and F53C11.3

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_506413.1	Gene:	F53C11.3 / 179872	WormBaseID:	WBGene00009973	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	55/199 - (27%)
Similarity:	93/199 - (46%)	Gaps:	18/199 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKA-GGKAY 68
            |.|.|:...:||...|:||.||...|..||::.:||:..:       .:...|:||..: ||...
Worm    22 GSLNGKVALVTGGGTGLGKAIATTFAHLGASVAIAARRLD-------VLEKTADEIRSSTGGVCE 79

  Fly    69 PCVVDVRDEQQVRSAVEAAVAKFGGI-DIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVS 132
            |..:||:|..:|..|.:|...|.|.. ||:||||:...:..|.......|..:.:|..:||..|:
Worm    80 PFQMDVKDPAKVAKAFDAVEKKLGHTPDILINNAAGNFIMATERLSPNAYGTIIDIVLKGTLHVT 144

  Fly   133 ----KVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVN 193
                :.|   :::...|.:|:|:...:.....|  .|...::|.|:......:|:|:...|:..|
Worm   145 TELGRRC---IQQKRGASVLSITTLYAQSGAPF--VVPSAVSKAGVENMTKSLASEWAKHGLRFN 204

  Fly   194 ALWP 197
            |:.|
Worm   205 AIAP 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	55/199 (28%)
		PRK08278	7..277	CDD:181349	54/197 (27%)
		SCP2	317..406	CDD:280250
F53C11.3	NP_506413.1	TER_DECR_SDR_a	40..275	CDD:187627	48/181 (27%)
F53C11.3	NP_506413.1	PRK07677	40..273	CDD:181077	48/181 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900