DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and dhrs-4

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_506230.1	Gene:	dhrs-4 / 179772	WormBaseID:	WBGene00010063	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	54/235 - (22%)
Similarity:	99/235 - (42%)	Gaps:	48/235 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKA 67
            |..:..|:...:|.|::|||..||.:...:||::|:.::..:          :..|.||....|.
Worm     4 NCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQK----------NVDEAIEYLKNKG 58

  Fly    68 YPCVVDV------RDEQQVRSAVEAAVAKFGGIDIVINNASA-ISLTNTPDTDMKRYDLMHNINT 125
            ...|..:      .|:|  :..|:..:.|||.|:|::||... .:..:..:...:.:|.:..:|.
Worm    59 LTKVAGIAGHIASTDDQ--KKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNV 121

  Fly   126 RGTFLVSKVCLPYL-KKSNHAHILNI------SPPLSMKPKWFGPHVAYTMAKYGMSMCVL---- 179
            :..|.::|:..|:: |:...|.|.|.      |||              .:|.||::...|
Worm   122 KAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPP--------------GIAAYGVTKTTLVGLT 172

  Fly   180 -GMAAEFKDEGISVNALWPRTAIHTAAIEML--TGPDSAK 216
             .:|.....:.|.||.:.| ..|.|...::|  .|.|:.|
Worm   173 RALAMGLAKDNIRVNGIAP-GVIKTKMSQVLWDGGEDAEK 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	53/233 (23%)
		PRK08278	7..277	CDD:181349	53/231 (23%)
		SCP2	317..406	CDD:280250
dhrs-4	NP_506230.1	SDR	9..260	CDD:330230	53/230 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810