DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and dhs-18

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_505812.1	Gene:	dhs-18 / 179529	WormBaseID:	WBGene00000981	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	195/283 - (68%)
Similarity:	231/283 - (81%)	Gaps:	5/283 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKA 67
            |||..||:|:||||||||||||||||.|:||||||||||||..|||||||||:||.|||||||.|
Worm     7 NTGFFAGKTVFITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYTAAAEIEKAGGHA 71

  Fly    68 YPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVS 132
            .|||||||||..|::||:|||.|||||||:||||||||||||.|||||||||||:||||||:|::
Worm    72 LPCVVDVRDEAAVKAAVDAAVKKFGGIDILINNASAISLTNTEDTDMKRYDLMHSINTRGTYLLT 136

  Fly   133 KVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWP 197
            |.|||||||..:.|:|||||||.|:.|||||||.|||||:||||||||...||:..||:||||||
Worm   137 KTCLPYLKKGKNPHVLNISPPLDMEAKWFGPHVGYTMAKFGMSMCVLGHHEEFRPYGIAVNALWP 201

  Fly   198 RTAIHTAAIEMLT-GPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEY 261
            .|||.|:|:|.|: |.||| .:||..||||:|||||:::.::.||.|.:|:|:|::.|||:..:|
Worm   202 LTAIWTSAMEFLSHGGDSA-GNRKASIMADSAYAILSKDSKKFTGNFLIDEELLQTQGITNFEQY 265

  Fly   262 ACFRENADKLMVDFFVEEKG-AP 283
            .|.  ....|:.||||.||. ||
Worm   266 ECV--PGSSLIPDFFVPEKSFAP 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	176/240 (73%)
		PRK08278	7..277	CDD:181349	186/270 (69%)
		SCP2	317..406	CDD:280250
dhs-18	NP_505812.1	PRK08278	11..279	CDD:181349	186/270 (69%)
dhs-18	NP_505812.1	adh_short	14..201	CDD:278532	146/186 (78%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156036
Domainoid	1	1.000	305	1.000	Domainoid score	I745
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H75204
Inparanoid	1	1.050	438	1.000	Inparanoid score	I939
Isobase	1	0.950	-	0	Normalized mean entropy	S1809
OMA	1	1.010	-	-		QHG63699
OrthoDB	1	1.010	-	-		D1361949at2759
OrthoFinder	1	1.000	-	-		FOG0005600
OrthoInspector	1	1.000	-	-		otm14130
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42808
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5337
SonicParanoid	1	1.000	-	-		X4574
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.890