DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5590 and Y47G6A.21

DIOPT Version :9

Sequence 1:	NP_651578.1	Gene:	CG5590 / 43325	FlyBaseID:	FBgn0039537	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001021764.1	Gene:	Y47G6A.21 / 171924	WormBaseID:	WBGene00021646	Length:	255	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	66/258 - (25%)
Similarity:	112/258 - (43%)	Gaps:	41/258 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYS----AAEEIEKAGGKAYPCVVDV 74
            |||||.||||..||..|:....:.:..:..:...::.....|    :|::|       ....|::
Worm     6 ITGASSGIGKGTALLFAKKKYQLSLTGRNTDSLKEVAALCISEGAISADDI-------LITAVEL 63

  Fly    75 RDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVSKVCLPYL 139
            ..::..::.|:|.|.|||.||.:||:|..:......|:.::.||.:.|:|.|....:::..||::
Worm    64 SSDEAPKAIVDATVQKFGRIDSLINSAGILRAGPVLDSGIEVYDELMNVNVRSLIRLTRAALPHI 128

  Fly   140 --KKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWPR---T 199
              .|....::.:|:.|..     |.....|.|:|..:......:|.|....|:.|||:.|.   |
Worm   129 ITTKGTVVNVSSINGPCP-----FAGVTYYCMSKSAVDQFTKCLALEMAPNGVRVNAVCPGVIVT 188

  Fly   200 AIHTAAIEMLTGPDSAKWSR------------KPEIMADAAYAILTREPRQS---TGQFFVDD 247
            .||.|     :|.|.|.::.            :|...::.|.|||.....:|   |||....|
Worm   189 NIHRA-----SGQDEATYAAFLEKSKTTHALGRPGTTSEVAEAILFLSSEKSSFTTGQLLKVD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5590	NP_651578.1	FabG	5..245	CDD:223959	65/254 (26%)
		PRK08278	7..277	CDD:181349	66/258 (26%)
		SCP2	317..406	CDD:280250
Y47G6A.21	NP_001021764.1	FabG	1..249	CDD:223959	66/258 (26%)
Y47G6A.21	NP_001021764.1	NADB_Rossmann	3..252	CDD:304358	66/258 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810