Protein Alignment Hsdl2 and LOC1275515

DIOPT Version :10

• Sequence 1: NP_651578.1
• Gene: Hsdl2 / 43325
• FlyBaseID: FBgn0039537
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: XP_314766.4
• Gene: LOC1275515 / 1275515
• VectorBaseID: AGAMI1_001579
• Length: 724
• Species: Anopheles gambiae
• Alignment Length: 732
• Identity: 138/732 - (18%)
• Similarity: 204/732 - (27%)
• Gaps: 351/732 - (47%)

  Fly     9 GRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIY---------SAAEEIEKAG 64
            ||.:.:|||..|:|:|.||..|..||.:||        ..|.|..:         ...|||..||
Mosquito    16 GRVVVVTGAGAGLGREYALLFASRGAKVVV--------NDLGGNFHGQGKSNAADKVVEEIRAAG 72

  Fly    65 GKAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAI---SLTNTPDTDMKRYDLMHNINTR 126
            |.|.|....|.:..::   |:.|:..||.||:::|||..:   ||....|.|   ::|:|:::.:
Mosquito    73 GVAVPDYNSVVEGDKI---VQTALENFGRIDVLVNNAGILRDRSLARISDED---WNLIHDVHLK 131

  Fly   127 GTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGIS 191
            |:||.::...|.:||.|:..|:..|....:... || ...|:.||.|:......:|.|.....|.
Mosquito   132 GSFLTTRAAWPVMKKQNYGRIIMTSSNSGVYGN-FG-QANYSAAKLGLVGLANTVAIEGAKNNIQ 194

  Fly   192 VNALWPRTAIHTAAIEMLTG--PDSAKWSRKPEIMADAAYAILTREPRQSTGQFF---------- 244
            .|.:.|     |||..|..|  |:......||:::|... |.|..|..:.||...
Mosquito   195 CNVIVP-----TAASRMTEGILPEILFNELKPKLIAPVV-AYLCHESCEDTGAIIESAAGWATKV 253

  Fly   245 -------------VDDE----------------------------------VLE----------- 251
                         :|::                                  |||
Mosquito   254 HFVRGRGCVLRTSIDEDVSPEYVQQVWNRVTDMSEAKRLNAIGEASLSLVGVLEKLRDGQNNENS 318

  Fly   252 -------------------SAGITDLTEYACFRENADKLMV--DFFV------------------ 277
                               .|.:||.|:.....||..:..|  .||:
Mosquito   319 VTETFRYGFKDAILYALGVGASVTDPTDLKFLYENNPEFAVLPTFFILPGLLAVMGSSLTASAIK 383

  Fly   278 -----------------------------------------------------EEKG-------- 281
                                                                 :|:|
Mosquito   384 HTTFDLTNILHGEQYIELFEAPATEGVLTTTSTVLDVVDKKSGALVITQSDSYDEQGTLVARNQS 448

  Fly   282 --------------------------------APVENEAAAEDAAAPASGGDV------------ 302
                                            |.||.......||.....||:
Mosquito   449 STFVVGAGNFNGKTKAGPEVKPLVPNPKRSPDASVEVPTHQNQAAVYRLSGDLNPMHIDPSFSAI 513

  Fly   303 ---KIPQL-------------------------------------------------------FR 309
               |:|.|                                                       ||
Mosquito   514 AGYKVPILHGLCTMGVSVKAVLKQFGGDDPTLFRAAKVRFSKPVLPGQTLRVDMWKEPNNRVCFR 578

  Fly   310 KIESLLSPEIVS------------------------------------------KTQAVFQFNIS 332
            .:....|.|::|                                          ...|||.:.|:
Mosquito   579 TVVVETSTEVLSGAYVDFKQIVIKPNMTAAVDLQSDAVFAGIKDRVAENEAKAKAINAVFLYKIT 643

  Fly   333 --GAEQGTWFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDF 395
              |.....|.|||||.....|........|.|:|:...:..::..|||:...|:|.|||||:|:.
Mosquito   644 SGGKVAKEWVLDLKNAKVYEGPVQGGGKADTTMTIADGDMIELALGKLQPQTAFMKGKLKIAGNI 708

  Fly   396 QKALKLEKLMKALKSKL 412
            ..|.||..|:|. ::||
Mosquito   709 MLAQKLAPLLKT-EAKL 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsdl2	NP_651578.1	PRK08278	7..277	CDD:181349	87/370 (24%)
		SCP2	306..408	CDD:442486	37/200 (19%)
LOC1275515	XP_314766.4	hydroxyacyl-CoA-like_DH_SDR_c-like	12..260	CDD:187611	75/265 (28%)
		PLN02864	322..599	CDD:178455	26/276 (9%)
		SCP2	617..719	CDD:460423	30/101 (30%)