DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc1 and Myl4

DIOPT Version :9

Sequence 1:	NP_001287569.1	Gene:	Mlc1 / 43323	FlyBaseID:	FBgn0002772	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	NP_001102965.1	Gene:	Myl4 / 688228	RGDID:	1591197	Length:	193	Species:	Rattus norvegicus

Alignment Length:	153	Identity:	59/153 - (38%)
Similarity:	82/153 - (53%)	Gaps:	9/153 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVPKREVENVEFVFEVMGSPGEG---IDAVDLGDALRALNLNPTLALIEKLGGTKK---RNEKKI 61
            |....::|..:..|.:......|   |.....||.||||..|||.|.:.::.|..|   .|.|.:
  Rat    43 DFSADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNSKTL 107

  Fly    62 KLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFA 126
            ..:.||||...:.:.||||.||||:|.|:::|||.|||::.|||:|.|..|||.:.:.:||.|..
  Rat   108 DFEMFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMSEAEVEQLLT 172

  Fly   127 DCMDPEDDEGFIPYSQFVQRLMS 149
               ..||..|.|.|..||:.:||
  Rat   173 ---GQEDANGCINYEAFVKHVMS 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc1	NP_001287569.1	PTZ00184	1..149	CDD:185504	57/151 (38%)
Mlc1	NP_001287569.1	EFh	84..148	CDD:298682	28/63 (44%)
Myl4	NP_001102965.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
Myl4	NP_001102965.1	PTZ00184	45..192	CDD:185504	56/149 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6207
eggNOG	1	0.900	-	-		E2759_KOG0030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920