DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc1 and cmlc1

DIOPT Version :9

Sequence 1:	NP_001287569.1	Gene:	Mlc1 / 43323	FlyBaseID:	FBgn0002772	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	NP_571767.2	Gene:	cmlc1 / 64671	ZFINID:	ZDB-GENE-030522-1	Length:	196	Species:	Danio rerio

Alignment Length:	153	Identity:	54/153 - (35%)
Similarity:	85/153 - (55%)	Gaps:	9/153 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVPKREVENVEFVFEVMGSPGEG---IDAVDLGDALRALNLNPTLA-LIEKLGGTK--KRNEKKI 61
            |....::|.....|.:......|   |.....||.:|||..|||.| ::..||..|  :.|.|.:
Zfish    46 DFSPDQIEEFRDAFTLFDETPTGEMKIRYAQCGDVMRALGHNPTNADVLTVLGKPKAEEMNTKYL 110

  Fly    62 KLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFA 126
            ..:.|||:...:.:.|:||.:|||:|.|:::|||.|||::.|||:|.|..|||.:.:::|:.|.|
Zfish   111 DFETFLPMLQHISRAKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEDEVDRLMA 175

  Fly   127 DCMDPEDDEGFIPYSQFVQRLMS 149
               ..||..|.|.|:.|::.::|
Zfish   176 ---GQEDANGCINYTSFIKHILS 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc1	NP_001287569.1	PTZ00184	1..149	CDD:185504	53/151 (35%)
Mlc1	NP_001287569.1	EFh	84..148	CDD:298682	27/63 (43%)
cmlc1	NP_571767.2	EFh_PEF	48..195	CDD:330173	52/149 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6866
eggNOG	1	0.900	-	-		E2759_KOG0030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920