DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mlc1 and MYL3

DIOPT Version :9

Sequence 1:	NP_001287569.1	Gene:	Mlc1 / 43323	FlyBaseID:	FBgn0002772	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	NP_000249.1	Gene:	MYL3 / 4634	HGNCID:	7584	Length:	195	Species:	Homo sapiens

Alignment Length:	121	Identity:	53/121 - (43%)
Similarity:	75/121 - (61%)	Gaps:	6/121 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GDALRALNLNPTLALIEKLGGTKKR---NEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYD 93
            ||.||||..|||.|.:.::.|..::   |.|.:..:.|||:...:.|.|:.|.||||:|.|:::|
Human    77 GDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFD 141

  Fly    94 KEENGTMLLAELQHALLALGESLDDEQVETLFADCMDPEDDEGFIPYSQFVQRLMS 149
            ||.|||::.|||:|.|..|||.|.:::||.|.|   ..||..|.|.|..||:.:||
Human   142 KEGNGTVMGAELRHVLATLGERLTEDEVEKLMA---GQEDSNGCINYEAFVKHIMS 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc1	NP_001287569.1	PTZ00184	1..149	CDD:185504	51/119 (43%)
Mlc1	NP_001287569.1	EFh	84..148	CDD:298682	30/63 (48%)
MYL3	NP_000249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
MYL3	NP_000249.1	PTZ00184	44..194	CDD:185504	51/119 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020