DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc1 and myl1

DIOPT Version :9

Sequence 1:	NP_001287569.1	Gene:	Mlc1 / 43323	FlyBaseID:	FBgn0002772	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	NP_956294.1	Gene:	myl1 / 336165	ZFINID:	ZDB-GENE-030131-8109	Length:	190	Species:	Danio rerio

Alignment Length:	151	Identity:	45/151 - (29%)
Similarity:	81/151 - (53%)	Gaps:	7/151 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVPKREVENVEFVFEVMGSPGEGIDAVD-LGDALRALNLNPTLALIEKLGGTKKRNE---KKIKL 63
            |..:.::|:....|.:....|:...|.: :.|.:|||..|||...:.|:.|....::   |::..
Zfish    42 DFTQDQMEDYREAFLLFDRVGDSKVAYNQIADIMRALGQNPTNKEVTKILGNPTADDMVNKRVDF 106

  Fly    64 DEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADC 128
            :.|||:...|.....:..|:|::|.|:::|||.|||::.|||:..|..|||.:.:.:::.|.
Zfish   107 EGFLPMLQVVINNPNKATYDDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMSEAEIDALM--- 168

  Fly   129 MDPEDDEGFIPYSQFVQRLMS 149
            ...||:.|.:.|..||:.:||
Zfish   169 QGQEDENGCVNYEAFVKHIMS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc1	NP_001287569.1	PTZ00184	1..149	CDD:185504	43/149 (29%)
Mlc1	NP_001287569.1	EFh	84..148	CDD:298682	23/63 (37%)
myl1	NP_956294.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
myl1	NP_956294.1	FRQ1	43..189	CDD:227455	42/148 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6866
eggNOG	1	0.900	-	-		E2759_KOG0030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.880