DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc1 and Myl1

DIOPT Version :9

Sequence 1:	NP_001287569.1	Gene:	Mlc1 / 43323	FlyBaseID:	FBgn0002772	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	NP_067260.1	Gene:	Myl1 / 17901	MGIID:	97269	Length:	188	Species:	Mus musculus

Alignment Length:	148	Identity:	62/148 - (41%)
Similarity:	90/148 - (60%)	Gaps:	7/148 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KREVENVEFVFEVMGSPGE-GIDAVDLGDALRALNLNPTLALIEKLGG---TKKRNEKKIKLDEF 66
            |.:.|:.:..|.:....|| .|....:||.||||..|||.|.::|:.|   .::.|.|||:.::|
Mouse    43 KEQQEDFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQF 107

  Fly    67 LPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADCMDP 131
            ||:...:...|:||.||||:|.|:::|||.|||::.|||:|.|..|||.:.:|:||.|.|   ..
Mouse   108 LPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLA---GQ 169

  Fly   132 EDDEGFIPYSQFVQRLMS 149
            ||..|.|.|..||:.:||
Mouse   170 EDSNGCINYEAFVKHIMS 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc1	NP_001287569.1	PTZ00184	1..149	CDD:185504	60/146 (41%)
Mlc1	NP_001287569.1	EFh	84..148	CDD:298682	30/63 (48%)
Myl1	NP_067260.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
Myl1	NP_067260.1	PTZ00184	39..187	CDD:185504	60/146 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I6299
eggNOG	1	0.900	-	-		E2759_KOG0030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910