DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpS10a and Plec

DIOPT Version :9

Sequence 1:NP_651576.1 Gene:RpS10a / 43321 FlyBaseID:FBgn0027494 Length:163 Species:Drosophila melanogaster
Sequence 2:NP_001157012.1 Gene:Plec / 18810 MGIID:1277961 Length:4691 Species:Mus musculus


Alignment Length:161 Identity:70/161 - (43%)
Similarity:88/161 - (54%) Gaps:15/161 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MFIPKANRVAIYEYLFKEGVLVAKKD-SPIQKHSELDKIPNLQVIKVMQSLNSRGWVKEQFAWRH 64
            |.:|.....||||.||:|||:||||| .|...|..:..:.||||::.|.||.:||.|:|.|||.|
Mouse     5 MLMPLDRLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLKARGLVRETFAWCH 69

  Fly    65 FYWLLTNEGIEELRRYLHLPPEIVPSTLTQT-----------TRSNAVRPRGGPGG---PGGGFG 115
            |||.||||||:.||:||||||||||::|.:.           .||..|:...||.|   ..|...
Mouse    70 FYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVIPARRRSPHVQTMQGPLGCPPKRGPLP 134

  Fly   116 GASKTDDDRSNYRRGPGAYGMDKKGDVGAGT 146
            ......::|..|||.....|..:...|.|.|
Mouse   135 AEDPAREERQVYRRKEREEGAPETPVVSATT 165

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpS10aNP_651576.1 S10_plectin 3..96 CDD:281497 54/104 (52%)
PlecNP_001157012.1 Globular 1. /evidence=ECO:0000250 1..1478 70/161 (43%)
S10_plectin 7..101 CDD:281497 54/93 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..161 12/47 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 167..186
Actin-binding 181..411
CH 186..293 CDD:237981
CH 308..406 CDD:278723
SPEC 667..761 CDD:197544
SPEC 763..941 CDD:238103
SPEC 1247..1437 CDD:238103
Central fibrous rod domain. /evidence=ECO:0000250 1479..2762
GBP_C <1497..1598 CDD:303769
Myosin_tail_1 1526..2713 CDD:279860
coiled coil 1588..1598 CDD:293879
ATP-synt_B <1620..1743 CDD:304375
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1626..1653
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1801..1835
SPEC 1871..2046 CDD:295325
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2100..2141
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2223..2317
GBP_C <2326..2510 CDD:303769
coiled coil 2477..2490 CDD:293879
coiled coil 2499..2510 CDD:293879
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2675..2728
Globular 2. /evidence=ECO:0000250 2763..4691
Plectin 2834..2875 CDD:279071
Plectin 2873..2913 CDD:279071
PLEC 2910..2946 CDD:197605
Plectin 2948..2989 CDD:279071
Plectin 3164..3203 CDD:279071
Plectin 3201..3241 CDD:279071
PLEC 3238..3274 CDD:197605
Plectin 3276..3315 CDD:279071
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 3312..3338
Plectin 3494..3534 CDD:279071
Plectin 3532..3572 CDD:279071
PLEC 3569..3600 CDD:197605
Plectin 3607..3648 CDD:279071
Plectin 3828..3869 CDD:279071
Plectin 3867..3907 CDD:279071
PLEC 3904..3940 CDD:197605
Plectin 3942..3983 CDD:279071
Plectin 4071..4112 CDD:279071
Plectin 4110..4150 CDD:279071
Plectin 4185..4226 CDD:279071
Binding to intermediate filaments. /evidence=ECO:0000250 4257..4307
Plectin <4287..4317 CDD:279071
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 4387..4420
PLEC 4419..4452 CDD:197605
Plectin 4454..4493 CDD:279071
Plectin 4530..4571 CDD:279071
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 4618..4691
4 X 4 AA tandem repeats of G-S-R-X 4632..4647
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5045
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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