DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and rhobtb4

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001352487.1	Gene:	rhobtb4 / 553415	ZFINID:	ZDB-GENE-060315-11	Length:	729	Species:	Danio rerio

Alignment Length:	211	Identity:	80/211 - (37%)
Similarity:	118/211 - (55%)	Gaps:	34/211 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RP----IKCVVVGDGTVGKTCMLISYTTDCFPGEY------VPTVF--DNYSAPMQ--------V 49
            ||    ||||||||..||||.::.:...:....:|      ||||:  |.|....:        |
Zfish    22 RPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVV 86

  Fly    50 DTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPII 114
            |.:.|||.||||.|  |:.:.|..:|.::||.::|:|:|:|:|..:|.:.|:|||||.||..|||
Zfish    87 DEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSLANPNSLRHVRTMWFPEIKHFCPRTPII 149

  Fly   115 LVGTKIDLR-EDRETLSGLAEQGLTPLK------REQGQKLANKIRAVKYMECSALTQRGLKPVF 172
            |||.::||| .|.:.::........|:|      .|:|.::|.:: .|.|.|.|.:.|.|:|.||
Zfish   150 LVGCQLDLRYADLDAVNRARRPLAKPIKPTDILPPERGHEVAKEL-GVPYYETSIVAQFGVKDVF 213

  Fly   173 EEAVRAVLRPEPLKRR 188
            :.|:||.|    :.||
Zfish   214 DNAIRAAL----ISRR 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	74/195 (38%)
rhobtb4	NP_001352487.1	RhoBTB	26..220	CDD:133275	74/196 (38%)
		BTB	<426..486	CDD:333434
		BTB	505..612	CDD:306997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810