DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and Miro

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001262895.1	Gene:	Miro / 42845	FlyBaseID:	FBgn0039140	Length:	673	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	57/207 - (27%)
Similarity:	88/207 - (42%)	Gaps:	37/207 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STGRPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQED 66
            |..:.::.::|||..||||.:::|..::.:| |.||...:..:.|..|...||...:.|.:..|.
  Fly     7 SQRKNVRILLVGDAGVGKTSLILSLVSEEYP-EEVPPRAEEITIPANVTPEQVPTSIVDFSAVEQ 70

  Fly    67 YDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHC-------PDA------------- 111
            .:........:..|..|.|:|....:.:.:||.|.|.::..|       .||
  Fly    71 SEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDTQREPI 135

  Fly   112 --PIILVGTKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEE 174
              ||:|||.||||.|.....|.||.....|           :|.:.  :||||.:...:..:|..
  Fly   136 RKPIVLVGNKIDLIEYSTMDSVLAIMEDYP-----------EIESC--VECSAKSLHNISEMFYY 187

  Fly   175 AVRAVLRP-EPL 185
            |.:|||.| .||
  Fly   188 AQKAVLHPTSPL 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	53/194 (27%)
Miro	NP_001262895.1	Miro1	10..195	CDD:206680	53/198 (27%)
		RHO	14..195	CDD:197554	53/194 (27%)
		EF_assoc_2	247..328	CDD:285547
		EF_assoc_1	367..437	CDD:285546
		Miro2	444..620	CDD:206679
		Ras	448..602	CDD:278499
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030