DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and RhoBTB

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001262107.1	Gene:	RhoBTB / 40249	FlyBaseID:	FBgn0036980	Length:	783	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	80/212 - (37%)
Similarity:	112/212 - (52%)	Gaps:	34/212 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKCVVVGDGTVGKTCMLIS------YTTDCFPGEYVPTVF--DNYSAPMQ--------VDTIQVS 55
            :|||:|||..||||.::.:      .:.......:||||:  |.|.....        ||.:.||
  Fly    14 VKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVS 78

  Fly    56 LGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKI 120
            |.||||.|  |:|:.|..:|.::||.|:|:|:|||.|..|....|||||:..|||.|:||||.|.
  Fly    79 LRLWDTFG--DHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKN 141

  Fly   121 DLR---EDRETLSGLAEQGL---TPLKR-----EQGQKLANKIRAVKYMECSALTQRGLKPVFEE 174
            |||   .|...||...|:|.   ..||.     ::.:.:|.:: .|.|.|.|..|..|:..|||.
  Fly   142 DLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKEL-GVAYYETSVFTYFGVNEVFEN 205

  Fly   175 AVRAVLRPEPLKRRQRK 191
            |:|:.|    :.|||::
  Fly   206 AIRSAL----IARRQQR 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	76/199 (38%)
RhoBTB	NP_001262107.1	RhoBTB	12..210	CDD:133275	76/198 (38%)
		RHO	16..211	CDD:197554	75/197 (38%)
		BTB	<392..446	CDD:295341
		BTB	481..575	CDD:279045
		BTB	485..582	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466337
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840