DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and Rhobtb2

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	XP_036014493.1	Gene:	Rhobtb2 / 246710	MGIID:	2180557	Length:	750	Species:	Mus musculus

Alignment Length:	215	Identity:	82/215 - (38%)
Similarity:	121/215 - (56%)	Gaps:	34/215 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTGRP----IKCVVVGDGTVGKTCMLISYTTDCFPGEY------VPTVF--DNYSAPMQ----- 48
            |...||    ||||||||..||||.::.:...:....:|      ||||:  |.|....:
Mouse    27 MDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91

  Fly    49 ---VDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPD 110
               ||.:.|||.||||.|  |:.:.|..:|.::||.::|:|:|:|:|..:|.:.|||||||.||.
Mouse    92 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154

  Fly   111 APIILVGTKIDLR-EDRETLSGLAEQGLTPLK------REQGQKLANKIRAVKYMECSALTQRGL 168
            ||:||||.::||| .|.|.::........|:|      .|:|:::|.:: .:.|.|.|.:.|.|:
Mouse   155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVAQFGI 218

  Fly   169 KPVFEEAVRAVLRPEPLKRR 188
            |.||:.|:||.|    :.||
Mouse   219 KDVFDNAIRAAL----ISRR 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	75/195 (38%)
Rhobtb2	XP_036014493.1	RhoBTB	35..229	CDD:133275	75/196 (38%)
		BTB_POZ	272..497	CDD:365784
		BTB2_POZ_RHOBTB2	502..625	CDD:349668
		BACK_RHOBTB2	630..726	CDD:350606
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810