DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mtl and RHOBTB2

DIOPT Version :9

Sequence 1:NP_524533.1 Gene:Mtl / 43319 FlyBaseID:FBgn0039532 Length:195 Species:Drosophila melanogaster
Sequence 2:NP_001153508.1 Gene:RHOBTB2 / 23221 HGNCID:18756 Length:749 Species:Homo sapiens


Alignment Length:215 Identity:82/215 - (38%)
Similarity:121/215 - (56%) Gaps:34/215 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSTGRP----IKCVVVGDGTVGKTCMLISYTTDCFPGEY------VPTVF--DNYSAPMQ----- 48
            |...||    ||||||||..||||.::.:...:....:|      ||||:  |.|....:     
Human    27 MDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91

  Fly    49 ---VDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPD 110
               ||.:.|||.||||.|  |:.:.|..:|.::||.::|:|:|:|:|..:|.:.|||||||.||.
Human    92 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154

  Fly   111 APIILVGTKIDLR-EDRETLSGLAEQGLTPLK------REQGQKLANKIRAVKYMECSALTQRGL 168
            ||:||||.::||| .|.|.::........|:|      .|:|:::|.:: .:.|.|.|.:.|.|:
Human   155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVAQFGI 218

  Fly   169 KPVFEEAVRAVLRPEPLKRR 188
            |.||:.|:||.|    :.||
Human   219 KDVFDNAIRAAL----ISRR 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MtlNP_524533.1 RHO 9..182 CDD:197554 75/195 (38%)
RHOBTB2NP_001153508.1 RhoBTB 35..229 CDD:133275 75/196 (38%)
RHO 39..230 CDD:197554 74/193 (38%)
BTB 280..>327 CDD:295341
BTB <443..492 CDD:197585
BTB <443..490 CDD:295341
BTB 513..615 CDD:279045
BTB 523..615 CDD:197585
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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