DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and Rnd1

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_766200.1	Gene:	Rnd1 / 223881	MGIID:	2444878	Length:	232	Species:	Mus musculus

Alignment Length:	183	Identity:	73/183 - (39%)
Similarity:	104/183 - (56%)	Gaps:	4/183 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRP 72
            |.|:|||...|||.||.....||:|..||||||:||:|.::.:..:|.|.||||:|...||.:||
Mouse    15 KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYYDNVRP 79

  Fly    73 LSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGL 137
            |.|..:|..|:|:.::.|.:.::...||..||..:||...::|:|.|.|||.|..||..|:.|..
Mouse    80 LCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQ 144

  Fly   138 TPLKREQGQKLANKIRAVKYMECSALT-QRGLKPVFEEAVRAVLR---PEPLK 186
            .|:..|||..:|.::.|..|:|.||.| :..:..:|..|....|.   |.|.|
Mouse   145 APISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKSSPVPPK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	69/176 (39%)
Rnd1	NP_766200.1	P-loop_NTPase	1..232	CDD:304359	73/183 (40%)
		RHO	16..190	CDD:197554	69/173 (40%)
		Effector region. /evidence=ECO:0000255	42..50		6/7 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810