DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and Rac1

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001334459.1	Gene:	Rac1 / 19353	MGIID:	97845	Length:	211	Species:	Mus musculus

Alignment Length:	208	Identity:	136/208 - (65%)
Similarity:	165/208 - (79%)	Gaps:	19/208 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLR 71
            |||||||||.|||||:||||||:.|||||:|||||||||.:.||...|:||||||||||||||||
Mouse     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLR 68

  Fly    72 PLSYPQT-------------------DVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVG 117
            |||||||                   ||||||:|:.||:|||||.:|||||::||||:.||||||
Mouse    69 PLSYPQTVGDTCGKDRPSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVG 133

  Fly   118 TKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRP 182
            ||:|||:|::|:..|.|:.|||:...||..:|.:|.||||:|||||||||||.||:||:||||.|
Mouse   134 TKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 198

  Fly   183 EPLKRRQRKCLIM 195
            .|:|:|:||||::
Mouse   199 PPVKKRKRKCLLL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	126/191 (66%)
Rac1	NP_001334459.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100633
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720