DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and Rnd2

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_033838.1	Gene:	Rnd2 / 11858	MGIID:	1338755	Length:	227	Species:	Mus musculus

Alignment Length:	179	Identity:	79/179 - (44%)
Similarity:	117/179 - (65%)	Gaps:	2/179 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TGRPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDY 67
            :|| .|.|||||...|||.:|..:..|.:||.||||||:||:|..::|..::.|.:|||:|...|
Mouse     5 SGR-CKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68

  Fly    68 DRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGL 132
            |.:|||:||.:|..|||:.::.|.:.::|..||..|.:..||:|.::|||.|:|:|.|..||..|
Mouse    69 DNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLREL 133

  Fly   133 AEQGLTPLKREQGQKLANKIRAVKYMECSA-LTQRGLKPVFEEAVRAVL 180
            ::|.|.|:..|||..||.::.||.|:|||: .::|.::.||..|..|.|
Mouse   134 SKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	76/173 (44%)
Rnd2	NP_033838.1	Rnd2_Rho7	7..227	CDD:206736	78/177 (44%)
		Effector region. /evidence=ECO:0000255	36..44		6/7 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..227
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810