DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtl and rhobtb1

DIOPT Version :9

Sequence 1:	NP_524533.1	Gene:	Mtl / 43319	FlyBaseID:	FBgn0039532	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	XP_003199615.1	Gene:	rhobtb1 / 100537290	ZFINID:	ZDB-GENE-130530-871	Length:	687	Species:	Danio rerio

Alignment Length:	219	Identity:	80/219 - (36%)
Similarity:	118/219 - (53%)	Gaps:	42/219 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTGRP----IKCVVVGDGTVGKTCMLISYTTDCFPGEY------VPTVF--DNYSAPMQ----- 48
            |...||    ||||||||..||||.::.:...:....:|      ||||:  |.|....:
Zfish     1 MDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERS 65

  Fly    49 ---VDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPD 110
               ||.:.|||.||||.|  |:.:.|..:|.::||.::|:|:|:|:|..:|.:.||.||||.||.
Zfish    66 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYLEIKHFCPR 128

  Fly   111 APIILVGTKIDLR-EDRETLSGLAEQGLTPLKR----------EQGQKLANKIRAVKYMECSALT 164
            .|:||||.::||| .|.|.::    :...||.|          |.|:::|.:: .:.|.|.|...
Zfish   129 TPVILVGCQLDLRYADLEAVN----RARRPLSRPIKPGDILPPESGREVAKEL-GIPYYETSVFD 188

  Fly   165 QRGLKPVFEEAVRAVLRPEPLKRR 188
            |.|:|.:|:.|:||.|    :.||
Zfish   189 QFGIKDIFDNAIRAAL----ISRR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	73/199 (37%)
rhobtb1	XP_003199615.1	RhoBTB	9..203	CDD:133275	73/200 (37%)
		BTB	355..446	CDD:333434
		BTB	477..569	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810